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- NCIT_C148214 IAO_0000115 "A therapeutic cell-based cancer vaccine consisting of autologous dendritic cells (DCs) fused with autologous acute myeloid leukemia (AML) cells, with potential immunostimulatory and antineoplastic activities. The autologous AML/DC fusion vaccine is generated in vitro by mixing DCs and irradiated AML cells harvested from individual patients, in the presence of polyethylene glycol (PEG), to produce hybrid DC-leukemia fusion cells. Upon re-administration, the autologous AML/DC fusion vaccine may elicit a cytotoxic T-lymphocyte (CTL)-mediated antitumor immune response against a broad array of AML-associated antigens, which may lead to AML cell lysis." @default.
- NCIT_C148214 NCIT_NHC0 "C148214" @default.
- NCIT_C148214 NCIT_P106 "Cell" @default.
- NCIT_C148214 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C148214 NCIT_P107 "Autologous AML/Dendritic Cell Fusion Vaccine" @default.
- NCIT_C148214 NCIT_P108 "Autologous AML/Dendritic Cell Fusion Vaccine" @default.
- NCIT_C148214 NCIT_P208 "CL550858" @default.
- NCIT_C148214 NCIT_P322 "CTRP" @default.
- NCIT_C148214 NCIT_P329 "792537" @default.
- NCIT_C148214 NCIT_P330 "792537" @default.
- NCIT_C148214 NCIT_P399 "792537" @default.
- NCIT_C148214 normalizedInformationContent "100" @default.
- NCIT_C148214 referenceCount "1" @default.
- NCIT_C148214 hasExactSynonym "Autologous AML/DC Fusion Vaccine" @default.
- NCIT_C148214 hasExactSynonym "Autologous AML/Dendritic Cell Fusion Vaccine" @default.
- NCIT_C148214 hasExactSynonym "Autologous DC/AML Fusion Vaccine" @default.
- NCIT_C148214 hasExactSynonym "Autologous Dendritic Cell/AML Fusion Vaccine" @default.
- NCIT_C148214 hasExactSynonym "DC/AML Fusion Cell Vaccine" @default.
- NCIT_C148214 inSubset NCIT_C116977 @default.
- NCIT_C148214 inSubset NCIT_C116978 @default.
- NCIT_C148214 inSubset NCIT_C128784 @default.
- NCIT_C148214 inSubset NCIT_C176424 @default.
- NCIT_C148214 type Class @default.
- NCIT_C148214 isDefinedBy ncit.owl @default.
- NCIT_C148214 label "Autologous AML/Dendritic Cell Fusion Vaccine" @default.
- NCIT_C148214 subClassOf NCIT_C129820 @default.
- NCIT_C148214 subClassOf NCIT_C148214 @default.
- NCIT_C148214 subClassOf NCIT_C1663 @default.
- NCIT_C148214 subClassOf NCIT_C1908 @default.
- NCIT_C148214 subClassOf NCIT_C1909 @default.
- NCIT_C148214 subClassOf NCIT_C274 @default.
- NCIT_C148214 subClassOf NCIT_C28308 @default.
- NCIT_C148214 subClassOf NCIT_C28310 @default.
- NCIT_C148214 subClassOf NCIT_C307 @default.
- NCIT_C148214 subClassOf NCIT_C308 @default.
- NCIT_C148214 subClassOf NCIT_C923 @default.