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- NCIT_C148520 IAO_0000115 "An orally bioavailable antagonist of the androgen receptor (AR), with potential antineoplastic activity. Upon oral administration, AR antagonist BAY 1161116 specifically binds to AR, inhibits AR activation, and prevents AR-mediated signaling. This inhibits cell growth in AR-overexpressing tumor cells. AR is overexpressed in prostate cancers and is involved in proliferation, survival and chemoresistance of tumor cells." @default.
- NCIT_C148520 NCIT_A32 NCIT_C1909 @default.
- NCIT_C148520 NCIT_NHC0 "C148520" @default.
- NCIT_C148520 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C148520 NCIT_P108 "Androgen Receptor Antagonist BAY 1161116" @default.
- NCIT_C148520 NCIT_P208 "CL551148" @default.
- NCIT_C148520 NCIT_P322 "GDC" @default.
- NCIT_C148520 NCIT_P329 "792679" @default.
- NCIT_C148520 NCIT_P330 "792679" @default.
- NCIT_C148520 NCIT_P375 "Androgen Receptor Antagonist BAY 1161116" @default.
- NCIT_C148520 NCIT_P399 "792679" @default.
- NCIT_C148520 normalizedInformationContent "100" @default.
- NCIT_C148520 referenceCount "1" @default.
- NCIT_C148520 hasExactSynonym "AR Antagonist BAY 1161116" @default.
- NCIT_C148520 hasExactSynonym "Androgen Receptor Antagonist BAY 1161116" @default.
- NCIT_C148520 hasExactSynonym "BAY 1161116" @default.
- NCIT_C148520 hasExactSynonym "BAY-1161116" @default.
- NCIT_C148520 hasExactSynonym "BAY1161116" @default.
- NCIT_C148520 inSubset NCIT_C128784 @default.
- NCIT_C148520 inSubset NCIT_C157711 @default.
- NCIT_C148520 inSubset NCIT_C157712 @default.
- NCIT_C148520 inSubset NCIT_C176424 @default.
- NCIT_C148520 inSubset NCIT_C177537 @default.
- NCIT_C148520 type Class @default.
- NCIT_C148520 isDefinedBy ncit.owl @default.
- NCIT_C148520 label "Androgen Receptor Antagonist BAY 1161116" @default.
- NCIT_C148520 subClassOf NCIT_C146993 @default.
- NCIT_C148520 subClassOf NCIT_C147908 @default.
- NCIT_C148520 subClassOf NCIT_C148520 @default.
- NCIT_C148520 subClassOf NCIT_C163758 @default.
- NCIT_C148520 subClassOf NCIT_C1908 @default.
- NCIT_C148520 subClassOf NCIT_C1909 @default.
- NCIT_C148520 subClassOf NCIT_C242 @default.
- NCIT_C148520 subClassOf NCIT_C274 @default.
- NCIT_C148520 subClassOf NCIT_C547 @default.