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- NCIT_C1492 IAO_0000115 "A recombinant therapeutic agent chemically identical to endogenous human GM-CSF except a leucine substitution in position 23. Binding to specific cell surface receptors, sargramostim modulates the proliferation and differentiation of a variety of hematopoietic progenitor cells with some specificity towards stimulation of leukocyte production and may reverse treatment-induced neutropenias. This agent also promotes antigen presentation, up-regulates antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin-2-mediated lymphokine-activated killer cell function; it may also augment host antitumoral immunity." @default.
- NCIT_C1492 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1492 NCIT_NHC0 "C1492" @default.
- NCIT_C1492 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1492 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1492 NCIT_P107 "Sargramostim" @default.
- NCIT_C1492 NCIT_P108 "Sargramostim" @default.
- NCIT_C1492 NCIT_P207 "C0216231" @default.
- NCIT_C1492 NCIT_P210 "123774-72-1" @default.
- NCIT_C1492 NCIT_P302 "Melanoma; Neutropenia-chemotherapy induced" @default.
- NCIT_C1492 NCIT_P319 "5TAA004E22" @default.
- NCIT_C1492 NCIT_P322 "CTRP" @default.
- NCIT_C1492 NCIT_P322 "FDA" @default.
- NCIT_C1492 NCIT_P322 "GDC" @default.
- NCIT_C1492 NCIT_P325 "A substance that helps make more white blood cells, especially granulocytes, macrophages, and cells that become platelets. It is a cytokine that is a type of hematopoietic (blood-forming) agent." @default.
- NCIT_C1492 NCIT_P329 "40566" @default.
- NCIT_C1492 NCIT_P330 "40566" @default.
- NCIT_C1492 NCIT_P366 "Sargramostim" @default.
- NCIT_C1492 NCIT_P375 "Sargramostim" @default.
- NCIT_C1492 NCIT_P399 "40566" @default.
- NCIT_C1492 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1492 NCIT_R124 NCIT_C18992 @default.
- NCIT_C1492 NCIT_R124 NCIT_C19143 @default.
- NCIT_C1492 NCIT_R124 NCIT_C21124 @default.
- NCIT_C1492 NCIT_R124 NCIT_C40702 @default.
- NCIT_C1492 NCIT_R124 NCIT_C45547 @default.
- NCIT_C1492 NCIT_R125 NCIT_C16674 @default.
- NCIT_C1492 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1492 NCIT_R125 NCIT_C17937 @default.
- NCIT_C1492 NCIT_R125 NCIT_C18095 @default.
- NCIT_C1492 NCIT_R125 NCIT_C18839 @default.
- NCIT_C1492 NCIT_R125 NCIT_C21124 @default.
- NCIT_C1492 NCIT_R125 NCIT_C21128 @default.
- NCIT_C1492 NCIT_R125 NCIT_C21147 @default.
- NCIT_C1492 NCIT_R125 NCIT_C26280 @default.
- NCIT_C1492 NCIT_R125 NCIT_C40739 @default.
- NCIT_C1492 NCIT_R125 NCIT_C40839 @default.
- NCIT_C1492 NCIT_R125 NCIT_C40912 @default.
- NCIT_C1492 NCIT_R146 NCIT_C21176 @default.
- NCIT_C1492 NCIT_R146 NCIT_C26548 @default.
- NCIT_C1492 NCIT_R146 NCIT_C38991 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12219 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12508 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12519 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12529 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12530 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12533 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12547 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12549 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12551 @default.
- NCIT_C1492 NCIT_R72 NCIT_C12662 @default.
- NCIT_C1492 NCIT_R72 NCIT_C21599 @default.
- NCIT_C1492 NCIT_R72 NCIT_C32725 @default.
- NCIT_C1492 normalizedInformationContent "66.977498465658655" @default.
- NCIT_C1492 referenceCount "147" @default.
- NCIT_C1492 hasExactSynonym "23-L-Leucinecolony-Stimulating Factor 2" @default.
- NCIT_C1492 hasExactSynonym "DRG-0012" @default.
- NCIT_C1492 hasExactSynonym "Leukine" @default.
- NCIT_C1492 hasExactSynonym "Prokine" @default.
- NCIT_C1492 hasExactSynonym "SARGRAMOSTIM" @default.
- NCIT_C1492 hasExactSynonym "Sagramostim" @default.
- NCIT_C1492 hasExactSynonym "Sargramostatin" @default.
- NCIT_C1492 hasExactSynonym "Sargramostim" @default.
- NCIT_C1492 hasExactSynonym "rhu GM-CFS" @default.
- NCIT_C1492 hasExactSynonym "sargramostim" @default.
- NCIT_C1492 inSubset NCIT_C116977 @default.
- NCIT_C1492 inSubset NCIT_C116978 @default.
- NCIT_C1492 inSubset NCIT_C128784 @default.
- NCIT_C1492 inSubset NCIT_C157711 @default.
- NCIT_C1492 inSubset NCIT_C157712 @default.
- NCIT_C1492 inSubset NCIT_C173381 @default.
- NCIT_C1492 inSubset NCIT_C173383 @default.
- NCIT_C1492 inSubset NCIT_C176424 @default.
- NCIT_C1492 inSubset NCIT_C177537 @default.
- NCIT_C1492 inSubset NCIT_C63923 @default.
- NCIT_C1492 type Class @default.
- NCIT_C1492 isDefinedBy ncit.owl @default.
- NCIT_C1492 label "Sargramostim" @default.
- NCIT_C1492 subClassOf NCIT_C1283 @default.
- NCIT_C1492 subClassOf NCIT_C1288 @default.
- NCIT_C1492 subClassOf NCIT_C1492 @default.
- NCIT_C1492 subClassOf NCIT_C1908 @default.
- NCIT_C1492 subClassOf NCIT_C1909 @default.
- NCIT_C1492 subClassOf NCIT_C2395 @default.
- NCIT_C1492 subClassOf NCIT_C307 @default.
- NCIT_C1492 subClassOf NCIT_C308 @default.
- NCIT_C1492 subClassOf NCIT_C387 @default.
- NCIT_C1492 subClassOf NCIT_C530 @default.