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- NCIT_C150373 IAO_0000115 "An orally bioavailable fluorescent imaging agent composed of the near-infrared (NIR) fluorophore cyanine 5 (Cy5) linked to a seven-amino acid long peptide that specifically binds to the tumor-associated antigen (TAA) epithelial growth factor receptor (epidermal growth factor receptor; EGFR), that can potentially be used for the imaging of EGFR-expressing tumor cells. Upon oral administration of the fluorescent imaging agent QRH-882260 heptapeptide, the peptide moiety selectively binds to EGFR expressed on tumor cells in the gastrointestinal (GI) tract. Upon fluorescence imaging, EGFR-expressing tumor cells can be visualized. EGFR, a member of the epidermal growth factor receptor family, is overexpressed on the surfaces of various tumors cells." @default.
- NCIT_C150373 NCIT_NHC0 "C150373" @default.
- NCIT_C150373 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C150373 NCIT_P108 "Imaging Agent QRH-882260 Heptapeptide" @default.
- NCIT_C150373 NCIT_P208 "CL552178" @default.
- NCIT_C150373 NCIT_P319 "HL2W44VNI8" @default.
- NCIT_C150373 NCIT_P322 "FDA" @default.
- NCIT_C150373 NCIT_P329 "792736" @default.
- NCIT_C150373 NCIT_P330 "792736" @default.
- NCIT_C150373 NCIT_P399 "792736" @default.
- NCIT_C150373 normalizedInformationContent "100" @default.
- NCIT_C150373 referenceCount "1" @default.
- NCIT_C150373 hasExactSynonym "Fluorescence Peptide QRH-882260" @default.
- NCIT_C150373 hasExactSynonym "Fluorescently-labeled Peptide QRH-882260" @default.
- NCIT_C150373 hasExactSynonym "Gln-Arg-His-Lys-Pro-Arg-Glu-Gly-Gly-Gly-Ser-Lys(Cy5)-NH2" @default.
- NCIT_C150373 hasExactSynonym "Imaging Agent QRH-882260 Heptapeptide" @default.
- NCIT_C150373 hasExactSynonym "QRH-882260 Cy-5-labeled Heptapeptide" @default.
- NCIT_C150373 hasExactSynonym "QRH-882260" @default.
- NCIT_C150373 hasExactSynonym "QRHKPRE-GGGSK-(Cy5)-NH2" @default.
- NCIT_C150373 inSubset NCIT_C176424 @default.
- NCIT_C150373 inSubset NCIT_C63923 @default.
- NCIT_C150373 type Class @default.
- NCIT_C150373 isDefinedBy ncit.owl @default.
- NCIT_C150373 label "Imaging Agent QRH-882260 Heptapeptide" @default.
- NCIT_C150373 subClassOf NCIT_C150373 @default.
- NCIT_C150373 subClassOf NCIT_C1908 @default.
- NCIT_C150373 subClassOf NCIT_C1966 @default.
- NCIT_C150373 subClassOf NCIT_C390 @default.
- NCIT_C150373 subClassOf NCIT_C45678 @default.
- NCIT_C150373 subClassOf NCIT_C802 @default.