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- NCIT_C150375 IAO_0000115 "An inhibitor of the sodium-dependent glucose co-transporter (sodium-glucose transporter; sodium-glucose transport protein; sodium-glucose linked transporter; SGLT) family members 1 and 2 (SGLT1/2) with antihyperglycemic activity. By binding to and blocking SGLT1/2, licogliflozin suppresses the reabsorption of glucose in the proximal tubule within the kidneys and enhances urinary excretion of glucose. This normalizes blood glucose levels. SGLT1/2, parts of a transport system expressed in the proximal renal tubules, mediate the majority of renal glucose reabsorption from tubular fluid." @default.
- NCIT_C150375 NCIT_NHC0 "C150375" @default.
- NCIT_C150375 NCIT_P106 "Organic Chemical" @default.
- NCIT_C150375 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C150375 NCIT_P108 "Licogliflozin" @default.
- NCIT_C150375 NCIT_P208 "CL552172" @default.
- NCIT_C150375 NCIT_P210 "1291094-73-9" @default.
- NCIT_C150375 NCIT_P319 "57J06X6EI0" @default.
- NCIT_C150375 NCIT_P322 "FDA" @default.
- NCIT_C150375 NCIT_P329 "792743" @default.
- NCIT_C150375 NCIT_P330 "792743" @default.
- NCIT_C150375 NCIT_P399 "792743" @default.
- NCIT_C150375 normalizedInformationContent "100" @default.
- NCIT_C150375 referenceCount "1" @default.
- NCIT_C150375 hasExactSynonym "D-Glucitol, 1,5-Anhydro-1-C-(3-((2,3-dihydro-1,4-benzodioxin-6-yl)methyl)-4-ethylphenyl)-, (1S)-" @default.
- NCIT_C150375 hasExactSynonym "LICOGLIFLOZIN" @default.
- NCIT_C150375 hasExactSynonym "LIK 066" @default.
- NCIT_C150375 hasExactSynonym "LIK-066" @default.
- NCIT_C150375 hasExactSynonym "LIK066" @default.
- NCIT_C150375 hasExactSynonym "Licogliflozin" @default.
- NCIT_C150375 inSubset NCIT_C176424 @default.
- NCIT_C150375 inSubset NCIT_C63923 @default.
- NCIT_C150375 type Class @default.
- NCIT_C150375 isDefinedBy ncit.owl @default.
- NCIT_C150375 label "Licogliflozin" @default.
- NCIT_C150375 subClassOf NCIT_C150375 @default.
- NCIT_C150375 subClassOf NCIT_C1908 @default.
- NCIT_C150375 subClassOf NCIT_C1909 @default.
- NCIT_C150375 subClassOf NCIT_C29711 @default.
- NCIT_C150375 subClassOf NCIT_C471 @default.
- NCIT_C150375 subClassOf NCIT_C78276 @default.
- NCIT_C150375 subClassOf NCIT_C98083 @default.