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- NCIT_C150392 IAO_0000115 "A radiotracer composed of an integrin alphaVbeta6 (aVb6) binding peptide (BP) radiolabeled with the radionuclide fluorine F 18, with potential integrin aVb6 imaging activity using positron emission tomography (PET). Upon administration, the fluorine F 18 integrin aVb6-targeted peptide selectively binds to integrin aVb6-positive cancer cells. During PET, aVb6-expressing tumor cells can be visualized and the degree of tumor growth can be determined. Integrin aVb6, a cell adhesion and signaling receptor, is upregulated in certain cancer cell types and has been associated with increased proliferation, migration and invasion of tumor cells." @default.
- NCIT_C150392 NCIT_NHC0 "C150392" @default.
- NCIT_C150392 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C150392 NCIT_P108 "Fluorine F 18 Integrin Alpha v Beta 6-targeted Peptide" @default.
- NCIT_C150392 NCIT_P208 "CL552159" @default.
- NCIT_C150392 NCIT_P329 "792848" @default.
- NCIT_C150392 NCIT_P330 "792848" @default.
- NCIT_C150392 NCIT_P399 "792848" @default.
- NCIT_C150392 normalizedInformationContent "100" @default.
- NCIT_C150392 referenceCount "1" @default.
- NCIT_C150392 hasExactSynonym "18F-aVb6-BP" @default.
- NCIT_C150392 hasExactSynonym "18F-aVb6-Binding-Peptide" @default.
- NCIT_C150392 hasExactSynonym "18F-alphavbeta6-binding Peptide" @default.
- NCIT_C150392 hasExactSynonym "Fluorine F 18 Integrin Alpha v Beta 6-targeted Peptide" @default.
- NCIT_C150392 inSubset NCIT_C173381 @default.
- NCIT_C150392 inSubset NCIT_C173383 @default.
- NCIT_C150392 inSubset NCIT_C176424 @default.
- NCIT_C150392 type Class @default.
- NCIT_C150392 isDefinedBy ncit.owl @default.
- NCIT_C150392 label "Fluorine F 18 Integrin Alpha v Beta 6-targeted Peptide" @default.
- NCIT_C150392 subClassOf NCIT_C1446 @default.
- NCIT_C150392 subClassOf NCIT_C150392 @default.
- NCIT_C150392 subClassOf NCIT_C1908 @default.
- NCIT_C150392 subClassOf NCIT_C1909 @default.
- NCIT_C150392 subClassOf NCIT_C2124 @default.