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- NCIT_C150467 IAO_0000115 "A radioconjugate composed of PSMA-R2, a human prostate-specific membrane antigen (PSMA)-targeting ligand, conjugated to the beta-emitting radioisotope lutetium Lu 177 (177Lu), with potential antineoplastic activity against PSMA-expressing tumor cells. Upon intravenous administration of 177Lu-PSMA-R2, the PSMA-R2 moiety targets and binds to PSMA-expressing tumor cells. Upon binding, PSMA-expressing tumor cells are destroyed by 177Lu through the specific delivery of beta particle radiation. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on the majority of prostate tumor cells." @default.
- NCIT_C150467 NCIT_A32 NCIT_C1909 @default.
- NCIT_C150467 NCIT_A7 NCIT_C17796 @default.
- NCIT_C150467 NCIT_NHC0 "C150467" @default.
- NCIT_C150467 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C150467 NCIT_P107 "Lutetium Lu-177 PSMA-R2" @default.
- NCIT_C150467 NCIT_P108 "Lutetium Lu-177 PSMA-R2" @default.
- NCIT_C150467 NCIT_P208 "CL552202" @default.
- NCIT_C150467 NCIT_P322 "CTRP" @default.
- NCIT_C150467 NCIT_P322 "GDC" @default.
- NCIT_C150467 NCIT_P329 "793409" @default.
- NCIT_C150467 NCIT_P330 "793409" @default.
- NCIT_C150467 NCIT_P375 "Lutetium Lu-177 PSMA-R2" @default.
- NCIT_C150467 NCIT_P399 "793409" @default.
- NCIT_C150467 normalizedInformationContent "100" @default.
- NCIT_C150467 referenceCount "1" @default.
- NCIT_C150467 hasExactSynonym "177Lu-PSMA-R2" @default.
- NCIT_C150467 hasExactSynonym "177LuPSMA-R2" @default.
- NCIT_C150467 hasExactSynonym "Lu177-PSMA-R2" @default.
- NCIT_C150467 hasExactSynonym "Lutetium Lu-177 PSMA-R2" @default.
- NCIT_C150467 hasExactSynonym "Lutetium-177 PSMA-R2" @default.
- NCIT_C150467 inSubset NCIT_C116977 @default.
- NCIT_C150467 inSubset NCIT_C116978 @default.
- NCIT_C150467 inSubset NCIT_C128784 @default.
- NCIT_C150467 inSubset NCIT_C157711 @default.
- NCIT_C150467 inSubset NCIT_C157712 @default.
- NCIT_C150467 inSubset NCIT_C176424 @default.
- NCIT_C150467 inSubset NCIT_C177537 @default.
- NCIT_C150467 type Class @default.
- NCIT_C150467 isDefinedBy ncit.owl @default.
- NCIT_C150467 label "Lutetium Lu-177 PSMA-R2" @default.
- NCIT_C150467 subClassOf NCIT_C129819 @default.
- NCIT_C150467 subClassOf NCIT_C1446 @default.
- NCIT_C150467 subClassOf NCIT_C150467 @default.
- NCIT_C150467 subClassOf NCIT_C1908 @default.
- NCIT_C150467 subClassOf NCIT_C1909 @default.
- NCIT_C150467 subClassOf NCIT_C2124 @default.
- NCIT_C150467 subClassOf NCIT_C274 @default.