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- NCIT_C150511 IAO_0000115 "Genetically engineered human allogeneic T-lymphocytes that are transduced with a retroviral vector encoding a T-cell receptor (TCR) specific for the cancer/testis antigen NY-ESO-1, with potential antineoplastic activity. Upon isolation, transduction, expansion ex vivo and introduction into the patient, the allogeneic T-lymphocytes expressing NY-ESO-1-C259-specific TCR specifically target and bind to NY-ESO-1-overexpressing tumor cells. This may result in the specific cytotoxic T-lymphocyte (CTL) killing of NY-ESO-1-positive cancer cells. NY-ESO-1, a tumor-associated antigen (TAA), is expressed in normal testis and on the surface of various tumor cell types." @default.
- NCIT_C150511 NCIT_NHC0 "C150511" @default.
- NCIT_C150511 NCIT_P106 "Cell" @default.
- NCIT_C150511 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C150511 NCIT_P108 "Allogeneic T-lymphocytes Expressing NY-ESO-1-C259-specific TCR" @default.
- NCIT_C150511 NCIT_P208 "CL552287" @default.
- NCIT_C150511 NCIT_P329 "793046" @default.
- NCIT_C150511 NCIT_P330 "793046" @default.
- NCIT_C150511 NCIT_P399 "793046" @default.
- NCIT_C150511 normalizedInformationContent "100" @default.
- NCIT_C150511 referenceCount "1" @default.
- NCIT_C150511 hasExactSynonym "Allogeneic NY-ESO-1-C259 T-cells" @default.
- NCIT_C150511 hasExactSynonym "Allogeneic T-lymphocytes Expressing NY-ESO-1-C259-specific TCR" @default.
- NCIT_C150511 hasExactSynonym "NY-ESO-1 c259 T Cells" @default.
- NCIT_C150511 inSubset NCIT_C128784 @default.
- NCIT_C150511 inSubset NCIT_C176424 @default.
- NCIT_C150511 type Class @default.
- NCIT_C150511 isDefinedBy ncit.owl @default.
- NCIT_C150511 label "Allogeneic T-lymphocytes Expressing NY-ESO-1-C259-specific TCR" @default.
- NCIT_C150511 subClassOf NCIT_C129820 @default.
- NCIT_C150511 subClassOf NCIT_C129821 @default.
- NCIT_C150511 subClassOf NCIT_C129826 @default.
- NCIT_C150511 subClassOf NCIT_C138180 @default.
- NCIT_C150511 subClassOf NCIT_C142078 @default.
- NCIT_C150511 subClassOf NCIT_C150511 @default.
- NCIT_C150511 subClassOf NCIT_C154231 @default.
- NCIT_C150511 subClassOf NCIT_C1908 @default.
- NCIT_C150511 subClassOf NCIT_C1909 @default.
- NCIT_C150511 subClassOf NCIT_C1962 @default.
- NCIT_C150511 subClassOf NCIT_C274 @default.
- NCIT_C150511 subClassOf NCIT_C28676 @default.
- NCIT_C150511 subClassOf NCIT_C307 @default.
- NCIT_C150511 subClassOf NCIT_C308 @default.