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- NCIT_C150559 IAO_0000115 "An orally available platelet thrombopoietin receptor (TPOR; MPL) agonist, with potential megakaryopoiesis stimulating activity. Upon administration, avatrombopag binds to and stimulates TPOR, which may lead to the proliferation and differentiation of megakaryocytes from bone marrow progenitor cells. This increases the production of platelets and may prevent chemotherapy-induced thrombocytopenia (CIT). TPOR is a cytokine receptor and member of the hematopoietin receptor superfamily." @default.
- NCIT_C150559 NCIT_NHC0 "C150559" @default.
- NCIT_C150559 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C150559 NCIT_P108 "Avatrombopag" @default.
- NCIT_C150559 NCIT_P208 "CL552362" @default.
- NCIT_C150559 NCIT_P210 "570406-98-3" @default.
- NCIT_C150559 NCIT_P302 "N-acetylglutamate synthase (NAGS) Deficiency Hyperammonemia; thrombocytopenia in adults with chronic liver disease scheduled to undergo a procedure" @default.
- NCIT_C150559 NCIT_P319 "3H8GSZ4SQL" @default.
- NCIT_C150559 NCIT_P322 "FDA" @default.
- NCIT_C150559 normalizedInformationContent "100" @default.
- NCIT_C150559 referenceCount "1" @default.
- NCIT_C150559 hasExactSynonym "4-Piperidinecarboxylic Acid, 1-(3-Chloro-5-(((4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-2-thiazolyl)amino)carbonyl)-2-pyridinyl)-" @default.
- NCIT_C150559 hasExactSynonym "AKR 501" @default.
- NCIT_C150559 hasExactSynonym "AKR-501" @default.
- NCIT_C150559 hasExactSynonym "AS 1670542" @default.
- NCIT_C150559 hasExactSynonym "AVATROMBOPAG" @default.
- NCIT_C150559 hasExactSynonym "Avatrombopag" @default.
- NCIT_C150559 hasExactSynonym "Doptelet" @default.
- NCIT_C150559 hasExactSynonym "E5501" @default.
- NCIT_C150559 hasExactSynonym "YM 477" @default.
- NCIT_C150559 hasExactSynonym "YM477" @default.
- NCIT_C150559 inSubset NCIT_C63923 @default.
- NCIT_C150559 type Class @default.
- NCIT_C150559 isDefinedBy ncit.owl @default.
- NCIT_C150559 label "Avatrombopag" @default.
- NCIT_C150559 subClassOf NCIT_C150559 @default.
- NCIT_C150559 subClassOf NCIT_C1908 @default.
- NCIT_C150559 subClassOf NCIT_C1909 @default.
- NCIT_C150559 subClassOf NCIT_C78275 @default.