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- NCIT_C1519 IAO_0000115 "A quinoline-3-carboxamide with potential antineoplastic activity. Roquinimex inhibits endothelial cell proliferation, migration, and basement membrane invasion; reduces the secretion of the angiogenic factor tumor necrosis factor alpha by tumor-associated macrophages (TAMs); and inhibits angiogenesis. This agent is also an immune modulator that appears to alter cytokine profiles and enhance the activity of T cells, natural killer cells, and macrophages. (NCI04)" @default.
- NCIT_C1519 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1519 NCIT_NHC0 "C1519" @default.
- NCIT_C1519 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1519 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1519 NCIT_P108 "Roquinimex" @default.
- NCIT_C1519 NCIT_P207 "C0244748" @default.
- NCIT_C1519 NCIT_P210 "84088-42-6" @default.
- NCIT_C1519 NCIT_P319 "372T2944C0" @default.
- NCIT_C1519 NCIT_P322 "FDA" @default.
- NCIT_C1519 NCIT_P322 "GDC" @default.
- NCIT_C1519 NCIT_P329 "41410" @default.
- NCIT_C1519 NCIT_P330 "41410" @default.
- NCIT_C1519 NCIT_P350 "C18H16N2O3" @default.
- NCIT_C1519 NCIT_P366 "Roquinimex" @default.
- NCIT_C1519 NCIT_P375 "Roquinimex" @default.
- NCIT_C1519 NCIT_P399 "41410" @default.
- NCIT_C1519 normalizedInformationContent "100" @default.
- NCIT_C1519 referenceCount "1" @default.
- NCIT_C1519 hasExactSynonym "1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-3-quinolinecarboxanilide" @default.
- NCIT_C1519 hasExactSynonym "1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide" @default.
- NCIT_C1519 hasExactSynonym "FCF 89" @default.
- NCIT_C1519 hasExactSynonym "LS 2616" @default.
- NCIT_C1519 hasExactSynonym "Linomide" @default.
- NCIT_C1519 hasExactSynonym "N-Phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxamide" @default.
- NCIT_C1519 hasExactSynonym "ROQUINIMEX" @default.
- NCIT_C1519 hasExactSynonym "Roquinimex" @default.
- NCIT_C1519 inSubset NCIT_C128784 @default.
- NCIT_C1519 inSubset NCIT_C157711 @default.
- NCIT_C1519 inSubset NCIT_C157712 @default.
- NCIT_C1519 inSubset NCIT_C176424 @default.
- NCIT_C1519 inSubset NCIT_C177537 @default.
- NCIT_C1519 inSubset NCIT_C63923 @default.
- NCIT_C1519 type Class @default.
- NCIT_C1519 isDefinedBy ncit.owl @default.
- NCIT_C1519 label "Roquinimex" @default.
- NCIT_C1519 subClassOf NCIT_C1519 @default.
- NCIT_C1519 subClassOf NCIT_C1742 @default.
- NCIT_C1519 subClassOf NCIT_C1908 @default.
- NCIT_C1519 subClassOf NCIT_C1909 @default.
- NCIT_C1519 subClassOf NCIT_C1971 @default.
- NCIT_C1519 subClassOf NCIT_C2139 @default.
- NCIT_C1519 subClassOf NCIT_C274 @default.
- NCIT_C1519 subClassOf NCIT_C308 @default.