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- NCIT_C151936 IAO_0000115 "A preparation of human autologous peripheral blood lymphocytes (PBLs) that have been genetically engineered to express a T-cell receptor (TCR) that specifically targets the viral oncoprotein human papillomavirus type 16 (HPV-16) E6, with potential antineoplastic activity. Upon administration, the HPV E6 TCR genetically-modified T-cells target and bind to HPV-16 E6-expressing tumor cells, which leads to specific cytotoxic T-lymphocyte (CTL)-mediated killing of HPV-16 E6-positive tumor cells. HPV-16 E6, a cell surface glycoprotein, plays a key role in the tumorigenesis of various HPV-associated tumors and is absent from healthy human tissues." @default.
- NCIT_C151936 NCIT_A7 NCIT_C1397 @default.
- NCIT_C151936 NCIT_NHC0 "C151936" @default.
- NCIT_C151936 NCIT_P106 "Cell" @default.
- NCIT_C151936 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C151936 NCIT_P107 "Autologous E6 T Cell Receptor Genetically-modified T Cells" @default.
- NCIT_C151936 NCIT_P108 "Autologous E6 T Cell Receptor Genetically-modified T Cells" @default.
- NCIT_C151936 NCIT_P208 "CL553275" @default.
- NCIT_C151936 NCIT_P322 "CTRP" @default.
- NCIT_C151936 NCIT_P329 "793136" @default.
- NCIT_C151936 NCIT_P330 "793136" @default.
- NCIT_C151936 NCIT_P399 "793136" @default.
- NCIT_C151936 NCIT_R124 NCIT_C17828 @default.
- NCIT_C151936 NCIT_R124 NCIT_C17930 @default.
- NCIT_C151936 NCIT_R124 NCIT_C17937 @default.
- NCIT_C151936 NCIT_R124 NCIT_C18839 @default.
- NCIT_C151936 NCIT_R124 NCIT_C21124 @default.
- NCIT_C151936 NCIT_R124 NCIT_C45548 @default.
- NCIT_C151936 NCIT_R125 NCIT_C17828 @default.
- NCIT_C151936 NCIT_R125 NCIT_C17937 @default.
- NCIT_C151936 NCIT_R125 NCIT_C18095 @default.
- NCIT_C151936 NCIT_R125 NCIT_C18839 @default.
- NCIT_C151936 NCIT_R125 NCIT_C19053 @default.
- NCIT_C151936 NCIT_R125 NCIT_C21124 @default.
- NCIT_C151936 NCIT_R125 NCIT_C26280 @default.
- NCIT_C151936 NCIT_R125 NCIT_C40833 @default.
- NCIT_C151936 NCIT_R125 NCIT_C40912 @default.
- NCIT_C151936 NCIT_R72 NCIT_C104083 @default.
- NCIT_C151936 NCIT_R72 NCIT_C12219 @default.
- NCIT_C151936 NCIT_R72 NCIT_C12476 @default.
- NCIT_C151936 NCIT_R72 NCIT_C12508 @default.
- NCIT_C151936 NCIT_R72 NCIT_C12535 @default.
- NCIT_C151936 NCIT_R72 NCIT_C12542 @default.
- NCIT_C151936 NCIT_R72 NCIT_C12543 @default.
- NCIT_C151936 NCIT_R72 NCIT_C21599 @default.
- NCIT_C151936 NCIT_R72 NCIT_C32725 @default.
- NCIT_C151936 NCIT_R72 NCIT_C33061 @default.
- NCIT_C151936 NCIT_R72 NCIT_C38434 @default.
- NCIT_C151936 NCIT_R72 NCIT_C38439 @default.
- NCIT_C151936 NCIT_R72 NCIT_C39567 @default.
- NCIT_C151936 NCIT_R72 NCIT_C39568 @default.
- NCIT_C151936 normalizedInformationContent "100" @default.
- NCIT_C151936 referenceCount "1" @default.
- NCIT_C151936 hasExactSynonym "Autologous Anti-HPV-16 E6 TCR T Cells" @default.
- NCIT_C151936 hasExactSynonym "Autologous E6 T Cell Receptor Genetically-modified T Cells" @default.
- NCIT_C151936 hasExactSynonym "Autologous E6 TCR T Cells" @default.
- NCIT_C151936 hasExactSynonym "Autologous E6 TCR T-cells" @default.
- NCIT_C151936 hasExactSynonym "Autologous HPV-16 E6 TCR T Cells" @default.
- NCIT_C151936 inSubset NCIT_C116977 @default.
- NCIT_C151936 inSubset NCIT_C116978 @default.
- NCIT_C151936 inSubset NCIT_C128784 @default.
- NCIT_C151936 inSubset NCIT_C176424 @default.
- NCIT_C151936 type Class @default.
- NCIT_C151936 isDefinedBy ncit.owl @default.
- NCIT_C151936 label "Autologous E6 T Cell Receptor Genetically-modified T Cells" @default.
- NCIT_C151936 subClassOf NCIT_C129820 @default.
- NCIT_C151936 subClassOf NCIT_C129821 @default.
- NCIT_C151936 subClassOf NCIT_C129826 @default.
- NCIT_C151936 subClassOf NCIT_C138180 @default.
- NCIT_C151936 subClassOf NCIT_C142078 @default.
- NCIT_C151936 subClassOf NCIT_C151936 @default.
- NCIT_C151936 subClassOf NCIT_C154231 @default.
- NCIT_C151936 subClassOf NCIT_C1908 @default.
- NCIT_C151936 subClassOf NCIT_C1909 @default.
- NCIT_C151936 subClassOf NCIT_C1962 @default.
- NCIT_C151936 subClassOf NCIT_C274 @default.
- NCIT_C151936 subClassOf NCIT_C28681 @default.
- NCIT_C151936 subClassOf NCIT_C307 @default.
- NCIT_C151936 subClassOf NCIT_C308 @default.