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- NCIT_C1522 IAO_0000115 "An orally-active thiazolidinedione with antidiabetic and hepatotoxic properties and potential antineoplastic activity. Troglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. (NCI04)" @default.
- NCIT_C1522 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1522 NCIT_NHC0 "C1522" @default.
- NCIT_C1522 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1522 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1522 NCIT_P108 "Troglitazone" @default.
- NCIT_C1522 NCIT_P207 "C0245514" @default.
- NCIT_C1522 NCIT_P210 "97322-87-7" @default.
- NCIT_C1522 NCIT_P319 "I66ZZ0ZN0E" @default.
- NCIT_C1522 NCIT_P322 "FDA" @default.
- NCIT_C1522 NCIT_P322 "GDC" @default.
- NCIT_C1522 NCIT_P329 "42706" @default.
- NCIT_C1522 NCIT_P330 "42706" @default.
- NCIT_C1522 NCIT_P366 "Troglitazone" @default.
- NCIT_C1522 NCIT_P368 "CHEBI:9753" @default.
- NCIT_C1522 NCIT_P375 "Troglitazone" @default.
- NCIT_C1522 NCIT_P399 "42706" @default.
- NCIT_C1522 normalizedInformationContent "100" @default.
- NCIT_C1522 referenceCount "1" @default.
- NCIT_C1522 hasExactSynonym "5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-2,4-Thiazolidinedione" @default.
- NCIT_C1522 hasExactSynonym "5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione" @default.
- NCIT_C1522 hasExactSynonym "CI-991" @default.
- NCIT_C1522 hasExactSynonym "CS-045" @default.
- NCIT_C1522 hasExactSynonym "Prelay" @default.
- NCIT_C1522 hasExactSynonym "Rezulin" @default.
- NCIT_C1522 hasExactSynonym "Romozin" @default.
- NCIT_C1522 hasExactSynonym "TROGLITAZONE" @default.
- NCIT_C1522 hasExactSynonym "Troglitazone" @default.
- NCIT_C1522 inSubset NCIT_C128784 @default.
- NCIT_C1522 inSubset NCIT_C157711 @default.
- NCIT_C1522 inSubset NCIT_C157712 @default.
- NCIT_C1522 inSubset NCIT_C176424 @default.
- NCIT_C1522 inSubset NCIT_C177537 @default.
- NCIT_C1522 inSubset NCIT_C63923 @default.
- NCIT_C1522 type Class @default.
- NCIT_C1522 isDefinedBy ncit.owl @default.
- NCIT_C1522 label "Troglitazone" @default.
- NCIT_C1522 subClassOf NCIT_C1522 @default.
- NCIT_C1522 subClassOf NCIT_C1908 @default.
- NCIT_C1522 subClassOf NCIT_C1909 @default.
- NCIT_C1522 subClassOf NCIT_C1934 @default.
- NCIT_C1522 subClassOf NCIT_C2122 @default.
- NCIT_C1522 subClassOf NCIT_C274 @default.
- NCIT_C1522 subClassOf NCIT_C29711 @default.
- NCIT_C1522 subClassOf NCIT_C78276 @default.
- NCIT_C1522 subClassOf NCIT_C98241 @default.