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- NCIT_C152205 IAO_0000115 "A next-generation, semi-synthetic, cyclic lipopeptide and echinocandin derivative, with potential antifungal activity. Upon administration, rezafungin inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, which is essential for fungal cell wall synthesis, and results in decreased synthesis of beta(1,3)-D-glucan. This weakens the fungal cell wall thereby causing osmotic lysis, fungal cell wall rupture and fungal cell death." @default.
- NCIT_C152205 NCIT_A5 NCIT_C152206 @default.
- NCIT_C152205 NCIT_NHC0 "C152205" @default.
- NCIT_C152205 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C152205 NCIT_P107 "Rezafungin" @default.
- NCIT_C152205 NCIT_P108 "Rezafungin" @default.
- NCIT_C152205 NCIT_P208 "CL553409" @default.
- NCIT_C152205 NCIT_P210 "1396640-59-7" @default.
- NCIT_C152205 NCIT_P319 "G013B5478J" @default.
- NCIT_C152205 NCIT_P322 "CTRP" @default.
- NCIT_C152205 NCIT_P322 "FDA" @default.
- NCIT_C152205 NCIT_P399 "811726" @default.
- NCIT_C152205 normalizedInformationContent "100" @default.
- NCIT_C152205 referenceCount "1" @default.
- NCIT_C152205 hasExactSynonym "REZAFUNGIN" @default.
- NCIT_C152205 hasExactSynonym "Rezafungin" @default.
- NCIT_C152205 inSubset NCIT_C116977 @default.
- NCIT_C152205 inSubset NCIT_C116978 @default.
- NCIT_C152205 inSubset NCIT_C176424 @default.
- NCIT_C152205 inSubset NCIT_C63923 @default.
- NCIT_C152205 type Class @default.
- NCIT_C152205 isDefinedBy ncit.owl @default.
- NCIT_C152205 label "Rezafungin" @default.
- NCIT_C152205 subClassOf NCIT_C152205 @default.
- NCIT_C152205 subClassOf NCIT_C1908 @default.
- NCIT_C152205 subClassOf NCIT_C1909 @default.
- NCIT_C152205 subClassOf NCIT_C254 @default.
- NCIT_C152205 subClassOf NCIT_C514 @default.