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- NCIT_C152206 IAO_0000115 "The acetate form of rezafungin, a next-generation, semi-synthetic, cyclic lipopeptide and echinocandin derivative, with potential antifungal activity. Upon administration, rezafungin inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, which is essential for fungal cell wall synthesis, and results in decreased synthesis of beta(1,3)-D-glucan. This weakens the fungal cell wall thereby causing osmotic lysis, fungal cell wall rupture and fungal cell death." @default.
- NCIT_C152206 NCIT_A6 NCIT_C152205 @default.
- NCIT_C152206 NCIT_NHC0 "C152206" @default.
- NCIT_C152206 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C152206 NCIT_P108 "Rezafungin Acetate" @default.
- NCIT_C152206 NCIT_P208 "CL553410" @default.
- NCIT_C152206 NCIT_P210 "1631754-41-0" @default.
- NCIT_C152206 NCIT_P319 "W1U1TMN677" @default.
- NCIT_C152206 NCIT_P322 "FDA" @default.
- NCIT_C152206 normalizedInformationContent "100" @default.
- NCIT_C152206 referenceCount "1" @default.
- NCIT_C152206 hasExactSynonym "REZAFUNGIN ACETATE" @default.
- NCIT_C152206 hasExactSynonym "Rezafungin Acetate" @default.
- NCIT_C152206 inSubset NCIT_C63923 @default.
- NCIT_C152206 type Class @default.
- NCIT_C152206 isDefinedBy ncit.owl @default.
- NCIT_C152206 label "Rezafungin Acetate" @default.
- NCIT_C152206 subClassOf NCIT_C152206 @default.
- NCIT_C152206 subClassOf NCIT_C1908 @default.
- NCIT_C152206 subClassOf NCIT_C1909 @default.
- NCIT_C152206 subClassOf NCIT_C254 @default.
- NCIT_C152206 subClassOf NCIT_C514 @default.