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- NCIT_C152212 IAO_0000115 "A narrow-spectrum antibiotic with potential activity against Clostridioides difficile infection (CDI). Upon oral administration, ridinilazole exerts its bactericidal activity against C. difficile through inhibition of cell division. This suppresses bacterial toxin production and inhibits the associated inflammatory response. Compared to other antibiotics that treat C. difficile, ridinilazole does not deplete intestinal bacteria and preserves the intestinal bacterial activity and the associated bile acid metabolome." @default.
- NCIT_C152212 NCIT_NHC0 "C152212" @default.
- NCIT_C152212 NCIT_P106 "Antibiotic" @default.
- NCIT_C152212 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C152212 NCIT_P107 "Ridinilazole" @default.
- NCIT_C152212 NCIT_P108 "Ridinilazole" @default.
- NCIT_C152212 NCIT_P208 "CL553416" @default.
- NCIT_C152212 NCIT_P210 "308362-25-6" @default.
- NCIT_C152212 NCIT_P319 "06DX01190R" @default.
- NCIT_C152212 NCIT_P322 "CTRP" @default.
- NCIT_C152212 NCIT_P322 "FDA" @default.
- NCIT_C152212 normalizedInformationContent "100" @default.
- NCIT_C152212 referenceCount "1" @default.
- NCIT_C152212 hasExactSynonym "5,5'-Bi-1H-benzimidazole, 2,2'-Di-4-pyridinyl-" @default.
- NCIT_C152212 hasExactSynonym "RIDINILAZOLE" @default.
- NCIT_C152212 hasExactSynonym "Ridinilazole" @default.
- NCIT_C152212 hasExactSynonym "SMT-19969" @default.
- NCIT_C152212 hasExactSynonym "SMT19969" @default.
- NCIT_C152212 hasExactSynonym "WHO 10075" @default.
- NCIT_C152212 inSubset NCIT_C116977 @default.
- NCIT_C152212 inSubset NCIT_C116978 @default.
- NCIT_C152212 inSubset NCIT_C63923 @default.
- NCIT_C152212 type Class @default.
- NCIT_C152212 isDefinedBy ncit.owl @default.
- NCIT_C152212 label "Ridinilazole" @default.
- NCIT_C152212 subClassOf NCIT_C152212 @default.
- NCIT_C152212 subClassOf NCIT_C1908 @default.
- NCIT_C152212 subClassOf NCIT_C1909 @default.
- NCIT_C152212 subClassOf NCIT_C254 @default.
- NCIT_C152212 subClassOf NCIT_C258 @default.