Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C152539> ?p ?o ?g. }
Showing items 1 to 42 of
42
with 100 items per page.
- NCIT_C152539 IAO_0000115 "A hydroxamic acid-derived histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Tefinostat inhibits HDAC leading to an accumulation of highly acetylated histones, which may result in chromatin remodeling, inhibition of tumor oncogene transcription, inhibition of tumor cell division, and the induction of tumor cell apoptosis. HDAC, an enzyme upregulated in many tumor types, deacetylates chromatin histone proteins; this agent may specifically target HDACs in cells of the monocyte-macrophage lineage." @default.
- NCIT_C152539 NCIT_A32 NCIT_C1909 @default.
- NCIT_C152539 NCIT_A7 NCIT_C16682 @default.
- NCIT_C152539 NCIT_NHC0 "C152539" @default.
- NCIT_C152539 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C152539 NCIT_P108 "Tefinostat" @default.
- NCIT_C152539 NCIT_P207 "C2830214" @default.
- NCIT_C152539 NCIT_P210 "914382-60-8" @default.
- NCIT_C152539 NCIT_P319 "ZAU91150SB" @default.
- NCIT_C152539 NCIT_P322 "FDA" @default.
- NCIT_C152539 NCIT_P322 "GDC" @default.
- NCIT_C152539 NCIT_P329 "633696" @default.
- NCIT_C152539 NCIT_P330 "633696" @default.
- NCIT_C152539 NCIT_P375 "HDAC Inhibitor CHR-2845" @default.
- NCIT_C152539 NCIT_P375 "Tefinostat" @default.
- NCIT_C152539 NCIT_P399 "633696" @default.
- NCIT_C152539 normalizedInformationContent "100" @default.
- NCIT_C152539 referenceCount "1" @default.
- NCIT_C152539 hasExactSynonym "CHR 2845" @default.
- NCIT_C152539 hasExactSynonym "CHR-2845" @default.
- NCIT_C152539 hasExactSynonym "CHR2845" @default.
- NCIT_C152539 hasExactSynonym "TEFINOSTAT" @default.
- NCIT_C152539 hasExactSynonym "Tefinostat" @default.
- NCIT_C152539 inSubset NCIT_C128784 @default.
- NCIT_C152539 inSubset NCIT_C157711 @default.
- NCIT_C152539 inSubset NCIT_C157712 @default.
- NCIT_C152539 inSubset NCIT_C176424 @default.
- NCIT_C152539 inSubset NCIT_C177537 @default.
- NCIT_C152539 inSubset NCIT_C63923 @default.
- NCIT_C152539 type Class @default.
- NCIT_C152539 isDefinedBy ncit.owl @default.
- NCIT_C152539 label "Tefinostat" @default.
- NCIT_C152539 subClassOf NCIT_C129824 @default.
- NCIT_C152539 subClassOf NCIT_C129825 @default.
- NCIT_C152539 subClassOf NCIT_C152539 @default.
- NCIT_C152539 subClassOf NCIT_C163758 @default.
- NCIT_C152539 subClassOf NCIT_C1908 @default.
- NCIT_C152539 subClassOf NCIT_C1909 @default.
- NCIT_C152539 subClassOf NCIT_C1946 @default.
- NCIT_C152539 subClassOf NCIT_C2189 @default.
- NCIT_C152539 subClassOf NCIT_C274 @default.
- NCIT_C152539 subClassOf NCIT_C471 @default.