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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C1526> ?p ?o ?g. }

• NCIT_C1526 IAO_0000115 "A semi-synthetic, second-generation taxane derived from a compound found in the European yew tree, Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and cell death. This agent also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. Docetaxel has been studied for use as a radiation-sensitizing agent. (NCI04)" @default.
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• NCIT_C1526 NCIT_A7 NCIT_C20450 @default.
• NCIT_C1526 NCIT_NHC0 "C1526" @default.
• NCIT_C1526 NCIT_P106 "Organic Chemical" @default.
• NCIT_C1526 NCIT_P106 "Pharmacologic Substance" @default.
• NCIT_C1526 NCIT_P107 "Docetaxel" @default.
• NCIT_C1526 NCIT_P108 "Docetaxel" @default.
• NCIT_C1526 NCIT_P175 "628503" @default.
• NCIT_C1526 NCIT_P207 "C0246415" @default.
• NCIT_C1526 NCIT_P210 "148408-66-6" @default.
• NCIT_C1526 NCIT_P302 "Breast cancer; Esophageal cancer; Gastric cancer; Head/Neck cancers; Locally Advanced or Metastatic Non small-cell lung cancer; Ovarian cancer; Metastatic Prostate cancer" @default.
• NCIT_C1526 NCIT_P319 "15H5577CQD" @default.
• NCIT_C1526 NCIT_P322 "CTRP" @default.
• NCIT_C1526 NCIT_P322 "FDA" @default.
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• NCIT_C1526 NCIT_P322 "OORO" @default.
• NCIT_C1526 NCIT_P322 "PCDC" @default.
• NCIT_C1526 NCIT_P325 "A drug used together with other drugs to treat certain types of breast cancer, stomach cancer, prostate cancer, and certain types of head and neck cancer. It is also being studied in the treatment of other types of cancer. Docetaxel is a type of mitotic inhibitor." @default.
• NCIT_C1526 NCIT_P329 "41657" @default.
• NCIT_C1526 NCIT_P330 "41657" @default.
• NCIT_C1526 NCIT_P350 "C43H53NO14.3H2O" @default.
• NCIT_C1526 NCIT_P366 "Docetaxel" @default.
• NCIT_C1526 NCIT_P368 "CHEBI:59809" @default.
• NCIT_C1526 NCIT_P375 "Docetaxel" @default.
• NCIT_C1526 NCIT_P399 "41657" @default.
• NCIT_C1526 NCIT_R122 NCIT_C16484 @default.
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• NCIT_C1526 NCIT_R122 NCIT_C17573 @default.
• NCIT_C1526 NCIT_R122 NCIT_C20027 @default.
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• NCIT_C1526 NCIT_R122 NCIT_C28459 @default.
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• NCIT_C1526 NCIT_R122 NCIT_C46000 @default.
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• NCIT_C1526 NCIT_R124 NCIT_C40795 @default.
• NCIT_C1526 NCIT_R124 NCIT_C40798 @default.
• NCIT_C1526 NCIT_R125 NCIT_C16397 @default.
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• NCIT_C1526 NCIT_R125 NCIT_C16864 @default.
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• NCIT_C1526 NCIT_R125 NCIT_C17828 @default.
• NCIT_C1526 NCIT_R125 NCIT_C19829 @default.
• NCIT_C1526 NCIT_R125 NCIT_C20349 @default.
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• NCIT_C1526 NCIT_R125 NCIT_C28563 @default.
• NCIT_C1526 NCIT_R125 NCIT_C40777 @default.
• NCIT_C1526 NCIT_R125 NCIT_C41515 @default.
• NCIT_C1526 NCIT_R146 NCIT_C16492 @default.
• NCIT_C1526 NCIT_R146 NCIT_C17021 @default.
• NCIT_C1526 NCIT_R146 NCIT_C17219 @default.
• NCIT_C1526 NCIT_R146 NCIT_C18073 @default.
• NCIT_C1526 NCIT_R146 NCIT_C20027 @default.
• NCIT_C1526 NCIT_R146 NCIT_C26548 @default.
• NCIT_C1526 normalizedInformationContent "68.050265177258879" @default.
• NCIT_C1526 referenceCount "125" @default.
• NCIT_C1526 hasExactSynonym "DOCETAXEL" @default.
• NCIT_C1526 hasExactSynonym "Docecad" @default.
• NCIT_C1526 hasExactSynonym "Docetaxel" @default.
• NCIT_C1526 hasExactSynonym "N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol" @default.
• NCIT_C1526 hasExactSynonym "RP 56976" @default.
• NCIT_C1526 hasExactSynonym "RP56976" @default.
• NCIT_C1526 hasExactSynonym "Taxotere Injection Concentrate" @default.
• NCIT_C1526 hasExactSynonym "Taxotere" @default.
• NCIT_C1526 hasExactSynonym "[2aR-[2a alphaa,4beta,4a beta,6beta,9alpha,(alphaR*,betaS*),-11alpha,12alpha,12a alpha,12b alpha]]-beta-[[(1,1-dimethylethoxy)carbonyl]-amino]-alpha-hydroxybenzemepropanoic Acid 12b-(Acetyloxy)-12(benzyloxy)-2a,3,4,4a,5,6,8,10,11,12,12a,12b-dodecahydeo-4,-6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester" @default.
• NCIT_C1526 hasExactSynonym "docetaxel" @default.
• NCIT_C1526 inSubset NCIT_C116977 @default.
• NCIT_C1526 inSubset NCIT_C116978 @default.
• NCIT_C1526 inSubset NCIT_C128784 @default.
• NCIT_C1526 inSubset NCIT_C157711 @default.
• NCIT_C1526 inSubset NCIT_C157712 @default.
• NCIT_C1526 inSubset NCIT_C176424 @default.
• NCIT_C1526 inSubset NCIT_C177537 @default.
• NCIT_C1526 inSubset NCIT_C179478 @default.
• NCIT_C1526 inSubset NCIT_C179531 @default.
• NCIT_C1526 inSubset NCIT_C192234 @default.
• NCIT_C1526 inSubset NCIT_C63923 @default.
• NCIT_C1526 type Class @default.
• NCIT_C1526 isDefinedBy ncit.owl @default.
• NCIT_C1526 label "Docetaxel" @default.
• NCIT_C1526 subClassOf NCIT_C1490 @default.
• NCIT_C1526 subClassOf NCIT_C1526 @default.
• NCIT_C1526 subClassOf NCIT_C186664 @default.
• NCIT_C1526 subClassOf NCIT_C1908 @default.
• NCIT_C1526 subClassOf NCIT_C1909 @default.
• NCIT_C1526 subClassOf NCIT_C1913 @default.
• NCIT_C1526 subClassOf NCIT_C25974 @default.
• NCIT_C1526 subClassOf NCIT_C273 @default.
• NCIT_C1526 subClassOf NCIT_C274 @default.
• NCIT_C1526 subClassOf NCIT_C552 @default.
• NCIT_C1526 subClassOf NCIT_C616 @default.
• NCIT_C1526 subClassOf NCIT_C67437 @default.

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