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- NCIT_C152875 IAO_0000115 "A long-acting beta-2 adrenergic agonist, with bronchodilator activity. Upon administration, vilanterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells." @default.
- NCIT_C152875 NCIT_NHC0 "C152875" @default.
- NCIT_C152875 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C152875 NCIT_P108 "Vilanterol" @default.
- NCIT_C152875 NCIT_P207 "C2935023" @default.
- NCIT_C152875 NCIT_P210 "503068-34-6" @default.
- NCIT_C152875 NCIT_P319 "028LZY775B" @default.
- NCIT_C152875 NCIT_P322 "FDA" @default.
- NCIT_C152875 NCIT_P329 "804498" @default.
- NCIT_C152875 NCIT_P330 "804498" @default.
- NCIT_C152875 NCIT_P399 "804498" @default.
- NCIT_C152875 normalizedInformationContent "100" @default.
- NCIT_C152875 referenceCount "1" @default.
- NCIT_C152875 hasExactSynonym "GW 642444" @default.
- NCIT_C152875 hasExactSynonym "GW-642444" @default.
- NCIT_C152875 hasExactSynonym "GW642444" @default.
- NCIT_C152875 hasExactSynonym "VILANTEROL" @default.
- NCIT_C152875 hasExactSynonym "Vilanterol" @default.
- NCIT_C152875 inSubset NCIT_C176424 @default.
- NCIT_C152875 inSubset NCIT_C63923 @default.
- NCIT_C152875 type Class @default.
- NCIT_C152875 isDefinedBy ncit.owl @default.
- NCIT_C152875 label "Vilanterol" @default.
- NCIT_C152875 subClassOf NCIT_C152875 @default.
- NCIT_C152875 subClassOf NCIT_C1908 @default.
- NCIT_C152875 subClassOf NCIT_C1909 @default.
- NCIT_C152875 subClassOf NCIT_C29712 @default.
- NCIT_C152875 subClassOf NCIT_C29747 @default.
- NCIT_C152875 subClassOf NCIT_C319 @default.
- NCIT_C152875 subClassOf NCIT_C48149 @default.
- NCIT_C152875 subClassOf NCIT_C78272 @default.
- NCIT_C152875 subClassOf NCIT_C78273 @default.
- NCIT_C152875 subClassOf NCIT_C87053 @default.