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- NCIT_C152912 IAO_0000115 "An orally bioavailable protease-activated receptor-1 (PAR-1) antagonist, with antiplatelet activity. Upon oral administration, vorapaxar binds to PAR-1 expressed on platelets, and inhibits PAR-1-mediated platelet aggregation. Vorapaxar inhibits thrombin-induced and thrombin receptor agonist peptide (TRAP)-induced platelet aggregation, and does not inhibit platelet aggregation induced by adenosine diphosphate (ADP), collagen or a thromboxane mimetic." @default.
- NCIT_C152912 NCIT_A5 NCIT_C152913 @default.
- NCIT_C152912 NCIT_NHC0 "C152912" @default.
- NCIT_C152912 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C152912 NCIT_P108 "Vorapaxar" @default.
- NCIT_C152912 NCIT_P207 "C2974521" @default.
- NCIT_C152912 NCIT_P210 "618385-01-6" @default.
- NCIT_C152912 NCIT_P319 "ZCE93644N2" @default.
- NCIT_C152912 NCIT_P322 "FDA" @default.
- NCIT_C152912 normalizedInformationContent "100" @default.
- NCIT_C152912 referenceCount "1" @default.
- NCIT_C152912 hasExactSynonym "VORAPAXAR" @default.
- NCIT_C152912 hasExactSynonym "Vorapaxar" @default.
- NCIT_C152912 inSubset NCIT_C63923 @default.
- NCIT_C152912 type Class @default.
- NCIT_C152912 isDefinedBy ncit.owl @default.
- NCIT_C152912 label "Vorapaxar" @default.
- NCIT_C152912 subClassOf NCIT_C1327 @default.
- NCIT_C152912 subClassOf NCIT_C152912 @default.
- NCIT_C152912 subClassOf NCIT_C1908 @default.
- NCIT_C152912 subClassOf NCIT_C1909 @default.
- NCIT_C152912 subClassOf NCIT_C78274 @default.
- NCIT_C152912 subClassOf NCIT_C78275 @default.