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- NCIT_C152913 IAO_0000115 "The sulfate salt form of vorapaxar, an orally bioavailable protease-activated receptor-1 (PAR-1) antagonist, with antiplatelet activity. Upon oral administration, vorapaxar binds to PAR-1 expressed on platelets, and inhibits PAR-1-mediated platelet aggregation. Vorapaxar inhibits thrombin-induced and thrombin receptor agonist peptide (TRAP)-induced platelet aggregation, and does not inhibit platelet aggregation induced by adenosine diphosphate (ADP), collagen or a thromboxane mimetic." @default.
- NCIT_C152913 NCIT_A6 NCIT_C152912 @default.
- NCIT_C152913 NCIT_NHC0 "C152913" @default.
- NCIT_C152913 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C152913 NCIT_P108 "Vorapaxar Sulfate" @default.
- NCIT_C152913 NCIT_P207 "C3818693" @default.
- NCIT_C152913 NCIT_P210 "705260-08-8" @default.
- NCIT_C152913 NCIT_P319 "IN66038E6C" @default.
- NCIT_C152913 NCIT_P322 "FDA" @default.
- NCIT_C152913 normalizedInformationContent "100" @default.
- NCIT_C152913 referenceCount "1" @default.
- NCIT_C152913 hasExactSynonym "SCH 530348" @default.
- NCIT_C152913 hasExactSynonym "VORAPAXAR SULFATE" @default.
- NCIT_C152913 hasExactSynonym "Vorapaxar Sulfate" @default.
- NCIT_C152913 hasExactSynonym "Zontivity" @default.
- NCIT_C152913 inSubset NCIT_C63923 @default.
- NCIT_C152913 type Class @default.
- NCIT_C152913 isDefinedBy ncit.owl @default.
- NCIT_C152913 label "Vorapaxar Sulfate" @default.
- NCIT_C152913 subClassOf NCIT_C1327 @default.
- NCIT_C152913 subClassOf NCIT_C152913 @default.
- NCIT_C152913 subClassOf NCIT_C1908 @default.
- NCIT_C152913 subClassOf NCIT_C1909 @default.
- NCIT_C152913 subClassOf NCIT_C78274 @default.
- NCIT_C152913 subClassOf NCIT_C78275 @default.