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- NCIT_C153083 IAO_0000115 "A preparation of autologous CD8+ T lymphocytes targeting SLC45A2, a melanoma-associated antigen, with potential immunomodulating and antineoplastic activities. Following peripheral blood mononuclear cell (PBMC) collection and ex vivo expansion of SLC45A2-specific cytotoxic T-lymphocytes (CTLs), the autologous CD8+ SLC45A2-specific CTLs are re-infused into the patient, where they target and lyse SLC45A2-expressing tumor cells. While SLC45A2 is expressed by approximately 80% of cutaneous melanomas, its expression is limited in mature normal melanocytes, allowing high tumor selectivity and reduced potential for autoimmune toxicity." @default.
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- NCIT_C153083 NCIT_P107 "Autologous CD8+ SLC45A2-specific T Lymphocytes" @default.
- NCIT_C153083 NCIT_P108 "Autologous CD8+ SLC45A2-specific T Lymphocytes" @default.
- NCIT_C153083 NCIT_P208 "CL554229" @default.
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- NCIT_C153083 hasExactSynonym "Autologous CD8+ SLC45A2-specific T Lymphocytes" @default.
- NCIT_C153083 hasExactSynonym "Autologous SLC45A2-specific CTLs" @default.
- NCIT_C153083 hasExactSynonym "Autologous SLC45A2-specific Cytotoxic T Lymphocytes" @default.
- NCIT_C153083 inSubset NCIT_C116977 @default.
- NCIT_C153083 inSubset NCIT_C116978 @default.
- NCIT_C153083 inSubset NCIT_C128784 @default.
- NCIT_C153083 inSubset NCIT_C176424 @default.
- NCIT_C153083 type Class @default.
- NCIT_C153083 isDefinedBy ncit.owl @default.
- NCIT_C153083 label "Autologous CD8+ SLC45A2-specific T Lymphocytes" @default.
- NCIT_C153083 subClassOf NCIT_C142078 @default.
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