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- NCIT_C153095 IAO_0000115 "The succinate salt form of epitinib, an orally available epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. Upon administration, epitinib inhibits the activity of EGFR, thereby preventing EGFR-mediated signaling. This may lead to induction of cell death and inhibition of tumor growth in EGFR-overexpressing tumor cells. EGFR is a receptor tyrosine kinase (RTK) that is overexpressed in certain tumor types and plays a key role in tumor cell proliferation and vascularization." @default.
- NCIT_C153095 NCIT_A32 NCIT_C1909 @default.
- NCIT_C153095 NCIT_NHC0 "C153095" @default.
- NCIT_C153095 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C153095 NCIT_P108 "Epitinib Succinate" @default.
- NCIT_C153095 NCIT_P208 "CL554354" @default.
- NCIT_C153095 NCIT_P210 "2252334-12-4" @default.
- NCIT_C153095 NCIT_P319 "2138WW3F3R" @default.
- NCIT_C153095 NCIT_P322 "FDA" @default.
- NCIT_C153095 NCIT_P322 "GDC" @default.
- NCIT_C153095 NCIT_P329 "793471" @default.
- NCIT_C153095 NCIT_P330 "793471" @default.
- NCIT_C153095 NCIT_P375 "Epitinib Succinate" @default.
- NCIT_C153095 NCIT_P399 "793471" @default.
- NCIT_C153095 normalizedInformationContent "100" @default.
- NCIT_C153095 referenceCount "1" @default.
- NCIT_C153095 hasExactSynonym "EPITINIB SUCCINATE" @default.
- NCIT_C153095 hasExactSynonym "Epitinib Succinate" @default.
- NCIT_C153095 hasExactSynonym "HMPL 813" @default.
- NCIT_C153095 hasExactSynonym "HMPL-813" @default.
- NCIT_C153095 hasExactSynonym "HMPL813" @default.
- NCIT_C153095 inSubset NCIT_C128784 @default.
- NCIT_C153095 inSubset NCIT_C157711 @default.
- NCIT_C153095 inSubset NCIT_C157712 @default.
- NCIT_C153095 inSubset NCIT_C176424 @default.
- NCIT_C153095 inSubset NCIT_C177537 @default.
- NCIT_C153095 inSubset NCIT_C63923 @default.
- NCIT_C153095 type Class @default.
- NCIT_C153095 isDefinedBy ncit.owl @default.
- NCIT_C153095 label "Epitinib Succinate" @default.
- NCIT_C153095 subClassOf NCIT_C129824 @default.
- NCIT_C153095 subClassOf NCIT_C129825 @default.
- NCIT_C153095 subClassOf NCIT_C1404 @default.
- NCIT_C153095 subClassOf NCIT_C153095 @default.
- NCIT_C153095 subClassOf NCIT_C163758 @default.
- NCIT_C153095 subClassOf NCIT_C163952 @default.
- NCIT_C153095 subClassOf NCIT_C1908 @default.
- NCIT_C153095 subClassOf NCIT_C1909 @default.
- NCIT_C153095 subClassOf NCIT_C1967 @default.
- NCIT_C153095 subClassOf NCIT_C2167 @default.
- NCIT_C153095 subClassOf NCIT_C2189 @default.
- NCIT_C153095 subClassOf NCIT_C274 @default.
- NCIT_C153095 subClassOf NCIT_C471 @default.