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- NCIT_C153129 IAO_0000115 "A bispecific, human monoclonal antibody with potential antineoplastic activity. REGN4018 contains two antigen-recognition sites: one for human CD3, a T cell surface antigen that is part of the T cell receptor complex, and one for human mucin 16 (MUC16, cancer antigen 125; CA125; FLJ14303), a member of the mucin family of glycoproteins that is overexpressed by several epithelial cancers, including ovarian cancer. Upon administration, ubamatamab binds to both T-cells and MUC16-expressing tumor cells, which cross-links the T-cells to the tumor cells, and may result in a potent cytotoxic T-lymphocyte (CTL) response against the MUC16-expressing tumor cells." @default.
- NCIT_C153129 NCIT_A32 NCIT_C1909 @default.
- NCIT_C153129 NCIT_A7 NCIT_C71020 @default.
- NCIT_C153129 NCIT_NHC0 "C153129" @default.
- NCIT_C153129 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C153129 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C153129 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C153129 NCIT_P107 "Ubamatamab" @default.
- NCIT_C153129 NCIT_P108 "Ubamatamab" @default.
- NCIT_C153129 NCIT_P208 "CL554386" @default.
- NCIT_C153129 NCIT_P210 "2305629-50-7" @default.
- NCIT_C153129 NCIT_P319 "6BUL1G4D60" @default.
- NCIT_C153129 NCIT_P322 "CTRP" @default.
- NCIT_C153129 NCIT_P322 "FDA" @default.
- NCIT_C153129 NCIT_P322 "GDC" @default.
- NCIT_C153129 NCIT_P329 "793937" @default.
- NCIT_C153129 NCIT_P330 "793937" @default.
- NCIT_C153129 NCIT_P375 "Anti-MUC16/CD3 BiTE Antibody REGN4018" @default.
- NCIT_C153129 NCIT_P375 "Anti-MUC16/CD3 Bispecific Antibody REGN4018" @default.
- NCIT_C153129 NCIT_P399 "793937" @default.
- NCIT_C153129 NCIT_R124 NCIT_C17710 @default.
- NCIT_C153129 NCIT_R124 NCIT_C17828 @default.
- NCIT_C153129 NCIT_R124 NCIT_C18219 @default.
- NCIT_C153129 NCIT_R124 NCIT_C19986 @default.
- NCIT_C153129 NCIT_R124 NCIT_C40474 @default.
- NCIT_C153129 normalizedInformationContent "100" @default.
- NCIT_C153129 referenceCount "1" @default.
- NCIT_C153129 hasExactSynonym "Anti-MUC16 x Anti-CD3 REGN4018" @default.
- NCIT_C153129 hasExactSynonym "Anti-MUC16/CD3 Bispecific Antibody REGN4018" @default.
- NCIT_C153129 hasExactSynonym "REGN 4018" @default.
- NCIT_C153129 hasExactSynonym "REGN-4018" @default.
- NCIT_C153129 hasExactSynonym "REGN4018" @default.
- NCIT_C153129 hasExactSynonym "UBAMATAMAB" @default.
- NCIT_C153129 hasExactSynonym "Ubamatamab" @default.
- NCIT_C153129 inSubset NCIT_C116977 @default.
- NCIT_C153129 inSubset NCIT_C116978 @default.
- NCIT_C153129 inSubset NCIT_C128784 @default.
- NCIT_C153129 inSubset NCIT_C157711 @default.
- NCIT_C153129 inSubset NCIT_C157712 @default.
- NCIT_C153129 inSubset NCIT_C176424 @default.
- NCIT_C153129 inSubset NCIT_C177537 @default.
- NCIT_C153129 inSubset NCIT_C63923 @default.
- NCIT_C153129 type Class @default.
- NCIT_C153129 isDefinedBy ncit.owl @default.
- NCIT_C153129 label "Ubamatamab" @default.
- NCIT_C153129 subClassOf NCIT_C112883 @default.
- NCIT_C153129 subClassOf NCIT_C1454 @default.
- NCIT_C153129 subClassOf NCIT_C153129 @default.
- NCIT_C153129 subClassOf NCIT_C1908 @default.
- NCIT_C153129 subClassOf NCIT_C1909 @default.
- NCIT_C153129 subClassOf NCIT_C201282 @default.
- NCIT_C153129 subClassOf NCIT_C20401 @default.
- NCIT_C153129 subClassOf NCIT_C28227 @default.
- NCIT_C153129 subClassOf NCIT_C307 @default.
- NCIT_C153129 subClassOf NCIT_C308 @default.