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- NCIT_C153159 IAO_0000115 "A radioimmunoconjugate consisting of a humanized monoclonal antibody directed against prostate specific membrane antigen (PSMA) labeled with the alpha particle-emitting radioisotope actinium Ac-225, with potential antineoplastic activity. Upon administration, actinium Ac-225 anti-PSMA monoclonal antibody J591 binds to the extracellular domain of PSMA with high affinity, thereby delivering alpha radiation to PSMA expressing cells. PSMA, a type II membrane protein expressed in all types of prostatic tissues, is often overexpressed in tumor cells." @default.
- NCIT_C153159 NCIT_A32 NCIT_C1909 @default.
- NCIT_C153159 NCIT_A7 NCIT_C17796 @default.
- NCIT_C153159 NCIT_NHC0 "C153159" @default.
- NCIT_C153159 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C153159 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C153159 NCIT_P108 "Actinium Ac-225 Anti-PSMA Monoclonal Antibody J591" @default.
- NCIT_C153159 NCIT_P208 "CL554298" @default.
- NCIT_C153159 NCIT_P322 "GDC" @default.
- NCIT_C153159 NCIT_P329 "793676" @default.
- NCIT_C153159 NCIT_P330 "793676" @default.
- NCIT_C153159 NCIT_P375 "Actinium Ac-225 Anti-PSMA Monoclonal Antibody J591" @default.
- NCIT_C153159 NCIT_P399 "793676" @default.
- NCIT_C153159 normalizedInformationContent "100" @default.
- NCIT_C153159 referenceCount "1" @default.
- NCIT_C153159 hasExactSynonym "225Ac-J591" @default.
- NCIT_C153159 hasExactSynonym "Ac 225 MOAB J591" @default.
- NCIT_C153159 hasExactSynonym "Ac 225 Monoclonal Antibody J591" @default.
- NCIT_C153159 hasExactSynonym "Actinium Ac-225 Anti-PSMA Monoclonal Antibody J591" @default.
- NCIT_C153159 hasExactSynonym "Actinium Ac-225 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody J591" @default.
- NCIT_C153159 inSubset NCIT_C128784 @default.
- NCIT_C153159 inSubset NCIT_C157711 @default.
- NCIT_C153159 inSubset NCIT_C157712 @default.
- NCIT_C153159 inSubset NCIT_C176424 @default.
- NCIT_C153159 inSubset NCIT_C177537 @default.
- NCIT_C153159 type Class @default.
- NCIT_C153159 isDefinedBy ncit.owl @default.
- NCIT_C153159 label "Actinium Ac-225 Anti-PSMA Monoclonal Antibody J591" @default.
- NCIT_C153159 subClassOf NCIT_C129819 @default.
- NCIT_C153159 subClassOf NCIT_C1446 @default.
- NCIT_C153159 subClassOf NCIT_C1511 @default.
- NCIT_C153159 subClassOf NCIT_C1512 @default.
- NCIT_C153159 subClassOf NCIT_C153159 @default.
- NCIT_C153159 subClassOf NCIT_C1908 @default.
- NCIT_C153159 subClassOf NCIT_C1909 @default.
- NCIT_C153159 subClassOf NCIT_C200225 @default.
- NCIT_C153159 subClassOf NCIT_C2124 @default.
- NCIT_C153159 subClassOf NCIT_C274 @default.
- NCIT_C153159 subClassOf NCIT_C307 @default.
- NCIT_C153159 subClassOf NCIT_C308 @default.