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- NCIT_C153209 IAO_0000115 "A small molecule compound that depletes serum amyloid P component (SAP), with potential anti-amyloid activity. Upon injection, miridesap binds to circulating SAP, forming complexes that are rapidly cleared in the liver. SAP bound to amyloid deposits is in equilibrium with plasma SAP, and depletion of the latter should lead to the eventual removal of SAP from amyloid deposits as well. SAP is a universal component of amyloid deposits and contributes to the pathogenesis of amyloidosis." @default.
- NCIT_C153209 NCIT_NHC0 "C153209" @default.
- NCIT_C153209 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C153209 NCIT_P107 "Miridesap" @default.
- NCIT_C153209 NCIT_P108 "Miridesap" @default.
- NCIT_C153209 NCIT_P208 "CL554333" @default.
- NCIT_C153209 NCIT_P210 "224624-80-0" @default.
- NCIT_C153209 NCIT_P319 "WO97N24A47" @default.
- NCIT_C153209 NCIT_P322 "CTRP" @default.
- NCIT_C153209 NCIT_P322 "FDA" @default.
- NCIT_C153209 NCIT_P329 "794046" @default.
- NCIT_C153209 NCIT_P330 "794046" @default.
- NCIT_C153209 NCIT_P399 "794046" @default.
- NCIT_C153209 normalizedInformationContent "100" @default.
- NCIT_C153209 referenceCount "1" @default.
- NCIT_C153209 hasExactSynonym "(2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxohexanoyl]pyrrolidine-2-carboxylic acid" @default.
- NCIT_C153209 hasExactSynonym "CPHPC" @default.
- NCIT_C153209 hasExactSynonym "GSK 2315698" @default.
- NCIT_C153209 hasExactSynonym "GSK-2315698" @default.
- NCIT_C153209 hasExactSynonym "GSK2315698" @default.
- NCIT_C153209 hasExactSynonym "MIRIDESAP" @default.
- NCIT_C153209 hasExactSynonym "Miridesap" @default.
- NCIT_C153209 inSubset NCIT_C116977 @default.
- NCIT_C153209 inSubset NCIT_C116978 @default.
- NCIT_C153209 inSubset NCIT_C176424 @default.
- NCIT_C153209 inSubset NCIT_C63923 @default.
- NCIT_C153209 type Class @default.
- NCIT_C153209 isDefinedBy ncit.owl @default.
- NCIT_C153209 label "Miridesap" @default.
- NCIT_C153209 subClassOf NCIT_C153209 @default.
- NCIT_C153209 subClassOf NCIT_C1908 @default.
- NCIT_C153209 subClassOf NCIT_C1909 @default.
- NCIT_C153209 subClassOf NCIT_C78275 @default.