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- NCIT_C1533 IAO_0000115 "The disodium salt of a synthetic pyrimidine-based antifolate. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis." @default.
- NCIT_C1533 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1533 NCIT_A6 NCIT_C61614 @default.
- NCIT_C1533 NCIT_A7 NCIT_C17199 @default.
- NCIT_C1533 NCIT_NHC0 "C1533" @default.
- NCIT_C1533 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1533 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1533 NCIT_P107 "Pemetrexed Disodium" @default.
- NCIT_C1533 NCIT_P108 "Pemetrexed Disodium" @default.
- NCIT_C1533 NCIT_P207 "C0936142" @default.
- NCIT_C1533 NCIT_P210 "150399-23-8" @default.
- NCIT_C1533 NCIT_P302 "Malignant pleural mesothelioma; Non-small cell lung cancer" @default.
- NCIT_C1533 NCIT_P319 "2PKU919BA9" @default.
- NCIT_C1533 NCIT_P322 "CTRP" @default.
- NCIT_C1533 NCIT_P322 "FDA" @default.
- NCIT_C1533 NCIT_P322 "GDC" @default.
- NCIT_C1533 NCIT_P325 "A drug used alone or with another drug to treat certain types of non-small cell lung cancer and malignant pleural mesothelioma. It is being studied in the treatment of other types of cancer. Pemetrexed disodium blocks DNA synthesis and may kill cancer cells. It is a type of folate antagonist." @default.
- NCIT_C1533 NCIT_P329 "42328" @default.
- NCIT_C1533 NCIT_P330 "42328" @default.
- NCIT_C1533 NCIT_P350 "C20H19N5O6.2Na" @default.
- NCIT_C1533 NCIT_P366 "Pemetrexed" @default.
- NCIT_C1533 NCIT_P368 "CHEBI:63722" @default.
- NCIT_C1533 NCIT_P375 "Pemetrexed Disodium" @default.
- NCIT_C1533 NCIT_P399 "42328" @default.
- NCIT_C1533 normalizedInformationContent "79.546070929969886" @default.
- NCIT_C1533 referenceCount "22" @default.
- NCIT_C1533 hasExactSynonym "Alimta" @default.
- NCIT_C1533 hasExactSynonym "Almita" @default.
- NCIT_C1533 hasExactSynonym "LY231514" @default.
- NCIT_C1533 hasExactSynonym "N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt" @default.
- NCIT_C1533 hasExactSynonym "PEMETREXED DISODIUM" @default.
- NCIT_C1533 hasExactSynonym "Pemetrexed Disodium" @default.
- NCIT_C1533 hasExactSynonym "pemetrexed disodium" @default.
- NCIT_C1533 inSubset NCIT_C116977 @default.
- NCIT_C1533 inSubset NCIT_C116978 @default.
- NCIT_C1533 inSubset NCIT_C128784 @default.
- NCIT_C1533 inSubset NCIT_C157711 @default.
- NCIT_C1533 inSubset NCIT_C157712 @default.
- NCIT_C1533 inSubset NCIT_C176424 @default.
- NCIT_C1533 inSubset NCIT_C177537 @default.
- NCIT_C1533 inSubset NCIT_C63923 @default.
- NCIT_C1533 type Class @default.
- NCIT_C1533 isDefinedBy ncit.owl @default.
- NCIT_C1533 label "Pemetrexed Disodium" @default.
- NCIT_C1533 subClassOf NCIT_C1533 @default.
- NCIT_C1533 subClassOf NCIT_C186664 @default.
- NCIT_C1533 subClassOf NCIT_C1908 @default.
- NCIT_C1533 subClassOf NCIT_C1909 @default.
- NCIT_C1533 subClassOf NCIT_C2021 @default.
- NCIT_C1533 subClassOf NCIT_C272 @default.
- NCIT_C1533 subClassOf NCIT_C274 @default.
- NCIT_C1533 subClassOf NCIT_C471 @default.
- NCIT_C1533 subClassOf NCIT_C511 @default.