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- NCIT_C153515 IAO_0000115 "A multi-epitope vaccine containing the following six class II MHC-restricted peptides: gp100, MelanA/MART-1, two tyrosinase peptides, and the cancer/testis antigens MAGE-A3 and MAGE-A1,2,3,6, with potential antineoplastic activity. Upon administration, melanoma helper peptides induce an antigen-specific, Th1-dominant, CD4+ T-cell response, potentially augmenting cytotoxic T-cell (CTL) responses and maintaining immunologic memory against tumor cells expressing melanoma-specific antigens. The 6MHP vaccine may also induce a CD8+ T-cell response through epitope spreading, potentially priming subsequent immune responses against tumor cells." @default.
- NCIT_C153515 NCIT_A7 NCIT_C104501 @default.
- NCIT_C153515 NCIT_A7 NCIT_C104511 @default.
- NCIT_C153515 NCIT_A7 NCIT_C104519 @default.
- NCIT_C153515 NCIT_A7 NCIT_C17513 @default.
- NCIT_C153515 NCIT_A7 NCIT_C33992 @default.
- NCIT_C153515 NCIT_A7 NCIT_C41037 @default.
- NCIT_C153515 NCIT_NHC0 "C153515" @default.
- NCIT_C153515 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C153515 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C153515 NCIT_P107 "6 Melanoma Helper Peptide Vaccine" @default.
- NCIT_C153515 NCIT_P108 "6 Melanoma Helper Peptide Vaccine" @default.
- NCIT_C153515 NCIT_P208 "CL554890" @default.
- NCIT_C153515 NCIT_P322 "CTRP" @default.
- NCIT_C153515 NCIT_P329 "794177" @default.
- NCIT_C153515 NCIT_P330 "794177" @default.
- NCIT_C153515 NCIT_P399 "794177" @default.
- NCIT_C153515 normalizedInformationContent "100" @default.
- NCIT_C153515 referenceCount "1" @default.
- NCIT_C153515 hasExactSynonym "6 Melanoma Helper Peptide Vaccine" @default.
- NCIT_C153515 hasExactSynonym "6MHP Vaccine" @default.
- NCIT_C153515 hasExactSynonym "6MHP" @default.
- NCIT_C153515 inSubset NCIT_C116977 @default.
- NCIT_C153515 inSubset NCIT_C116978 @default.
- NCIT_C153515 inSubset NCIT_C128784 @default.
- NCIT_C153515 inSubset NCIT_C176424 @default.
- NCIT_C153515 type Class @default.
- NCIT_C153515 isDefinedBy ncit.owl @default.
- NCIT_C153515 label "6 Melanoma Helper Peptide Vaccine" @default.
- NCIT_C153515 subClassOf NCIT_C129820 @default.
- NCIT_C153515 subClassOf NCIT_C153515 @default.
- NCIT_C153515 subClassOf NCIT_C1663 @default.
- NCIT_C153515 subClassOf NCIT_C1908 @default.
- NCIT_C153515 subClassOf NCIT_C1909 @default.
- NCIT_C153515 subClassOf NCIT_C2517 @default.
- NCIT_C153515 subClassOf NCIT_C274 @default.
- NCIT_C153515 subClassOf NCIT_C307 @default.
- NCIT_C153515 subClassOf NCIT_C308 @default.
- NCIT_C153515 subClassOf NCIT_C923 @default.