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- NCIT_C155888 IAO_0000115 "A preparation of autologous T-lymphocytes that have been genetically modified and transduced with a lentiviral vector expressing a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD19 and containing, as of yet undisclosed co-stimulatory signaling domains, with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR T-cells IM19 target and bind to CD19-expressing tumor cells, thereby inducing selective toxicity in CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies." @default.
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- NCIT_C155888 NCIT_P108 "Autologous Anti-CD19 CAR T-cells IM19" @default.
- NCIT_C155888 NCIT_P208 "CL562698" @default.
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- NCIT_C155888 NCIT_P329 "794869" @default.
- NCIT_C155888 NCIT_P330 "794869" @default.
- NCIT_C155888 NCIT_P375 "Autologous Anti-CD19 CAR T-cells IM19" @default.
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- NCIT_C155888 normalizedInformationContent "100" @default.
- NCIT_C155888 referenceCount "1" @default.
- NCIT_C155888 hasExactSynonym "Autologous Anti-CD19 CAR T-cells IM19" @default.
- NCIT_C155888 hasExactSynonym "Autologous Anti-CD19 CAR-T Cells IM19" @default.
- NCIT_C155888 hasExactSynonym "Autologous CD19-specific CAR-T Cells IM19" @default.
- NCIT_C155888 hasExactSynonym "IM19" @default.
- NCIT_C155888 inSubset NCIT_C128784 @default.
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- NCIT_C155888 inSubset NCIT_C177537 @default.
- NCIT_C155888 type Class @default.
- NCIT_C155888 isDefinedBy ncit.owl @default.
- NCIT_C155888 label "Autologous Anti-CD19 CAR T-cells IM19" @default.
- NCIT_C155888 subClassOf NCIT_C129820 @default.
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