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- NCIT_C155898 IAO_0000115 "A radioconjugate composed of a nanobody directed against human epidermal growth factor receptor 2 (HER2, EGFR2, ERBB2) that is linked, through the macrocyclic chelating agent 1,4,7-triazacyclononane-N,N',N''-triacetic acid (NOTA) to the radionuclide gallium (Ga) 68, with potential use in diagnostic imaging using positron emission tomography/computed tomography (PET/CT). Upon administration of gallium Ga 68-NOTA-anti-HER2 Nanobody VHH1, the anti-HER2 antibody moiety targets and binds to HER2-expressing cells. This facilitates both detection of HER2-expressing tumor cells and assessment of responses to HER2-targeted chemotherapeutic agents during PET/CT. HER2, a tyrosine kinase is overexpressed on the cell surfaces of various tumor cell types." @default.
- NCIT_C155898 NCIT_NHC0 "C155898" @default.
- NCIT_C155898 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C155898 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C155898 NCIT_P108 "Gallium Ga 68-NOTA-anti-HER2 Nanobody VHH1" @default.
- NCIT_C155898 NCIT_P208 "CL562773" @default.
- NCIT_C155898 NCIT_P329 "794875" @default.
- NCIT_C155898 NCIT_P330 "794875" @default.
- NCIT_C155898 NCIT_P399 "794875" @default.
- NCIT_C155898 normalizedInformationContent "100" @default.
- NCIT_C155898 referenceCount "1" @default.
- NCIT_C155898 hasExactSynonym "68Ga-HER2-Nanobody VHH1" @default.
- NCIT_C155898 hasExactSynonym "68Ga-NOTA-2Rs15d" @default.
- NCIT_C155898 hasExactSynonym "68Ga-NOTA-anti-HER2 VHH1" @default.
- NCIT_C155898 hasExactSynonym "Gallium Ga 68-NOTA-anti-HER2 Nanobody VHH1" @default.
- NCIT_C155898 hasExactSynonym "Gallium Ga 68-NOTA-anti-HER2-VHH1" @default.
- NCIT_C155898 hasExactSynonym "VHH1" @default.
- NCIT_C155898 inSubset NCIT_C176424 @default.
- NCIT_C155898 type Class @default.
- NCIT_C155898 isDefinedBy ncit.owl @default.
- NCIT_C155898 label "Gallium Ga 68-NOTA-anti-HER2 Nanobody VHH1" @default.
- NCIT_C155898 subClassOf NCIT_C1446 @default.
- NCIT_C155898 subClassOf NCIT_C1511 @default.
- NCIT_C155898 subClassOf NCIT_C1512 @default.
- NCIT_C155898 subClassOf NCIT_C155898 @default.
- NCIT_C155898 subClassOf NCIT_C1908 @default.
- NCIT_C155898 subClassOf NCIT_C1909 @default.
- NCIT_C155898 subClassOf NCIT_C2124 @default.
- NCIT_C155898 subClassOf NCIT_C307 @default.
- NCIT_C155898 subClassOf NCIT_C308 @default.