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- NCIT_C156710 IAO_0000115 "A long-acting, extended-release microsphere formulation of the acetate form of goserelin, a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH), with potential antineoplastic activity. Upon administration, goserelin binds to and activates pituitary gonadotropin-releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in an extended-release formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function." @default.
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- NCIT_C156710 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C156710 NCIT_P108 "Goserelin Acetate Extended-release Microspheres LY01005" @default.
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- NCIT_C156710 hasExactSynonym "Goserelin Acetate Extended-release Microspheres LY01005" @default.
- NCIT_C156710 hasExactSynonym "Goserelin Acetate Extended-release Microspheres" @default.
- NCIT_C156710 hasExactSynonym "LY 01005" @default.
- NCIT_C156710 hasExactSynonym "LY-01005" @default.
- NCIT_C156710 hasExactSynonym "LY01005" @default.
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- NCIT_C156710 label "Goserelin Acetate Extended-release Microspheres LY01005" @default.
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