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- NCIT_C156735 IAO_0000115 "An orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, taragarestrant specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells." @default.
- NCIT_C156735 NCIT_A32 NCIT_C1909 @default.
- NCIT_C156735 NCIT_A7 NCIT_C38361 @default.
- NCIT_C156735 NCIT_NHC0 "C156735" @default.
- NCIT_C156735 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C156735 NCIT_P108 "Taragarestrant" @default.
- NCIT_C156735 NCIT_P208 "CL935902" @default.
- NCIT_C156735 NCIT_P210 "2118899-51-5" @default.
- NCIT_C156735 NCIT_P319 "KD4HIM135V" @default.
- NCIT_C156735 NCIT_P322 "FDA" @default.
- NCIT_C156735 NCIT_P322 "GDC" @default.
- NCIT_C156735 NCIT_P329 "795596" @default.
- NCIT_C156735 NCIT_P330 "795596" @default.
- NCIT_C156735 NCIT_P375 "SERD D-0502" @default.
- NCIT_C156735 NCIT_P399 "795596" @default.
- NCIT_C156735 normalizedInformationContent "100" @default.
- NCIT_C156735 referenceCount "1" @default.
- NCIT_C156735 hasExactSynonym "(2E)-3-(3,5-Dichloro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1hpyrido(3,4-b)indol-1-yl)phenyl)prop-2-enoic acid" @default.
- NCIT_C156735 hasExactSynonym "2-Propenoic acid, 3-(3,5-dichloro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-1H-pyrido(3,4-b)indol-1-yl)phenyl)-, (2E)-" @default.
- NCIT_C156735 hasExactSynonym "D 0502" @default.
- NCIT_C156735 hasExactSynonym "D-0502" @default.
- NCIT_C156735 hasExactSynonym "D0502" @default.
- NCIT_C156735 hasExactSynonym "SERD D-0502" @default.
- NCIT_C156735 hasExactSynonym "Selective Estrogen Receptor Downregulator D-0502" @default.
- NCIT_C156735 hasExactSynonym "TARAGARESTRANT" @default.
- NCIT_C156735 hasExactSynonym "Taragarestrant" @default.
- NCIT_C156735 inSubset NCIT_C128784 @default.
- NCIT_C156735 inSubset NCIT_C157711 @default.
- NCIT_C156735 inSubset NCIT_C157712 @default.
- NCIT_C156735 inSubset NCIT_C176424 @default.
- NCIT_C156735 inSubset NCIT_C177537 @default.
- NCIT_C156735 inSubset NCIT_C63923 @default.
- NCIT_C156735 type Class @default.
- NCIT_C156735 isDefinedBy ncit.owl @default.
- NCIT_C156735 label "Taragarestrant" @default.
- NCIT_C156735 subClassOf NCIT_C129818 @default.
- NCIT_C156735 subClassOf NCIT_C147908 @default.
- NCIT_C156735 subClassOf NCIT_C156735 @default.
- NCIT_C156735 subClassOf NCIT_C163758 @default.
- NCIT_C156735 subClassOf NCIT_C1908 @default.
- NCIT_C156735 subClassOf NCIT_C1909 @default.
- NCIT_C156735 subClassOf NCIT_C2116 @default.
- NCIT_C156735 subClassOf NCIT_C274 @default.
- NCIT_C156735 subClassOf NCIT_C481 @default.
- NCIT_C156735 subClassOf NCIT_C547 @default.