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- NCIT_C157025 IAO_0000115 "An intravenous (IV) amino acid (AA) solution containing the cationic amino acids L-lysine and L-arginine, with radioprotective activity. Upon IV administration of the AA solution, L-lysine and L-arginine are specifically taken up by the kidneys. This protects the kidneys from toxicity by certain co-administered radio-labeled peptides as they compete with radio-labeled peptides for renal uptake. This reduces uptake of the radio-labeled peptides by the kidneys and decreases their renal retention. It also increases the target-to-kidney ratio of the radio-labeled peptides, thereby reducing radiation exposure to the kidneys and preventing nephrotoxicity." @default.
- NCIT_C157025 NCIT_NHC0 "C157025" @default.
- NCIT_C157025 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C157025 NCIT_P107 "L-lysine/L-arginine-containing Amino Acid" @default.
- NCIT_C157025 NCIT_P108 "L-lysine/L-arginine-containing Amino Acid" @default.
- NCIT_C157025 NCIT_P208 "CL936065" @default.
- NCIT_C157025 NCIT_P322 "CTRP" @default.
- NCIT_C157025 NCIT_P329 "796487" @default.
- NCIT_C157025 NCIT_P330 "796487" @default.
- NCIT_C157025 NCIT_P399 "796487" @default.
- NCIT_C157025 normalizedInformationContent "100" @default.
- NCIT_C157025 referenceCount "1" @default.
- NCIT_C157025 hasExactSynonym "Amino Acid Renal Protectant Solution" @default.
- NCIT_C157025 hasExactSynonym "Amino Acid Solution-containing L-lysine and L-arginine" @default.
- NCIT_C157025 hasExactSynonym "Intravenous L-lysine/L-arginine-containing Amino Acid Solution" @default.
- NCIT_C157025 hasExactSynonym "L-lysine/L-arginine AA Solution" @default.
- NCIT_C157025 hasExactSynonym "L-lysine/L-arginine-containing Amino Acid" @default.
- NCIT_C157025 hasExactSynonym "Lysine-Arginine Amino Acid Solution" @default.
- NCIT_C157025 hasExactSynonym "Lysine/Arginine Amino Acid Solution" @default.
- NCIT_C157025 hasExactSynonym "Radioprotective Amino Acid Solution" @default.
- NCIT_C157025 inSubset NCIT_C116977 @default.
- NCIT_C157025 inSubset NCIT_C116978 @default.
- NCIT_C157025 inSubset NCIT_C128784 @default.
- NCIT_C157025 inSubset NCIT_C176424 @default.
- NCIT_C157025 type Class @default.
- NCIT_C157025 isDefinedBy ncit.owl @default.
- NCIT_C157025 label "L-lysine/L-arginine-containing Amino Acid" @default.
- NCIT_C157025 subClassOf NCIT_C157025 @default.
- NCIT_C157025 subClassOf NCIT_C1908 @default.
- NCIT_C157025 subClassOf NCIT_C1909 @default.
- NCIT_C157025 subClassOf NCIT_C2099 @default.
- NCIT_C157025 subClassOf NCIT_C26170 @default.
- NCIT_C157025 subClassOf NCIT_C797 @default.