Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C157344> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- NCIT_C157344 IAO_0000115 "A preparation of autologous T-lymphocytes transduced with a retroviral vector encoding a T-cell receptor (TCR) sequence specific for CT-RCC-1, a tumor-associated antigen (TAA) and HLA-A11-restricted peptide encoded by human endogenous retrovirus (HERV) type E as well as a truncated CD34 chain (CD34t), with potential antineoplastic activity. Upon isolation, transduction, expansion ex vivo and re-introduction into the patient, the autologous CT-RCC-1 HERV-E-TCR-transduced-HLA-A11-restricted CD8+/CD34t+ T-cells bind to and induce selective toxicity in tumor cells expressing both the HLA-A11 allele and the CT-RCC-1 HERV-E antigen. The CD34t protein allows the transduced cells to be identified with an anti-CD34 antibody, and facilitates monitoring of the genetically modified T-cells following adoptive transfer. CT-RCC-1 HERV-E is a TAA found in a high percentage of clear cell renal cell carcinoma (ccRCC) cells." @default.
- NCIT_C157344 NCIT_NHC0 "C157344" @default.
- NCIT_C157344 NCIT_P106 "Cell" @default.
- NCIT_C157344 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C157344 NCIT_P107 "Autologous CT-RCC-1 HERV-E-TCR-transduced-HLA-A11-restricted CD8+/CD34t+ T-cells" @default.
- NCIT_C157344 NCIT_P108 "Autologous CT-RCC-1 HERV-E-TCR-transduced-HLA-A11-restricted CD8+/CD34t+ T-cells" @default.
- NCIT_C157344 NCIT_P208 "CL936969" @default.
- NCIT_C157344 NCIT_P322 "CTRP" @default.
- NCIT_C157344 NCIT_P329 "796813" @default.
- NCIT_C157344 NCIT_P330 "796813" @default.
- NCIT_C157344 NCIT_P399 "796813" @default.
- NCIT_C157344 NCIT_R124 NCIT_C17828 @default.
- NCIT_C157344 NCIT_R124 NCIT_C17930 @default.
- NCIT_C157344 NCIT_R124 NCIT_C17937 @default.
- NCIT_C157344 NCIT_R124 NCIT_C18839 @default.
- NCIT_C157344 NCIT_R124 NCIT_C21124 @default.
- NCIT_C157344 NCIT_R124 NCIT_C45548 @default.
- NCIT_C157344 NCIT_R125 NCIT_C17828 @default.
- NCIT_C157344 NCIT_R125 NCIT_C17937 @default.
- NCIT_C157344 NCIT_R125 NCIT_C18095 @default.
- NCIT_C157344 NCIT_R125 NCIT_C18839 @default.
- NCIT_C157344 NCIT_R125 NCIT_C19053 @default.
- NCIT_C157344 NCIT_R125 NCIT_C21124 @default.
- NCIT_C157344 NCIT_R125 NCIT_C26280 @default.
- NCIT_C157344 NCIT_R125 NCIT_C40833 @default.
- NCIT_C157344 NCIT_R125 NCIT_C40912 @default.
- NCIT_C157344 NCIT_R72 NCIT_C104083 @default.
- NCIT_C157344 NCIT_R72 NCIT_C12219 @default.
- NCIT_C157344 NCIT_R72 NCIT_C12476 @default.
- NCIT_C157344 NCIT_R72 NCIT_C12508 @default.
- NCIT_C157344 NCIT_R72 NCIT_C12535 @default.
- NCIT_C157344 NCIT_R72 NCIT_C12542 @default.
- NCIT_C157344 NCIT_R72 NCIT_C12543 @default.
- NCIT_C157344 NCIT_R72 NCIT_C21599 @default.
- NCIT_C157344 NCIT_R72 NCIT_C32725 @default.
- NCIT_C157344 NCIT_R72 NCIT_C33061 @default.
- NCIT_C157344 NCIT_R72 NCIT_C38434 @default.
- NCIT_C157344 NCIT_R72 NCIT_C38439 @default.
- NCIT_C157344 NCIT_R72 NCIT_C39567 @default.
- NCIT_C157344 NCIT_R72 NCIT_C39568 @default.
- NCIT_C157344 normalizedInformationContent "100" @default.
- NCIT_C157344 referenceCount "1" @default.
- NCIT_C157344 hasExactSynonym "Anti-CT-RCC-1 HERV-E-TCR-transduced-HLA-A11-restricted Autologous CD8+/CD34t+ T-cells (SY)" @default.
- NCIT_C157344 hasExactSynonym "Autologous CT-RCC-1 HERV-E-TCR-transduced-HLA-A11-restricted CD8+/CD34t+ T-cells" @default.
- NCIT_C157344 hasExactSynonym "Autologous CT-RCC-1 HERV-E-TCR-transduced-HLA-A11-restricted CD8+/CD34t+ T-lymphocytes" @default.
- NCIT_C157344 inSubset NCIT_C116977 @default.
- NCIT_C157344 inSubset NCIT_C116978 @default.
- NCIT_C157344 inSubset NCIT_C128784 @default.
- NCIT_C157344 inSubset NCIT_C176424 @default.
- NCIT_C157344 type Class @default.
- NCIT_C157344 isDefinedBy ncit.owl @default.
- NCIT_C157344 label "Autologous CT-RCC-1 HERV-E-TCR-transduced-HLA-A11-restricted CD8+/CD34t+ T-cells" @default.
- NCIT_C157344 subClassOf NCIT_C142078 @default.
- NCIT_C157344 subClassOf NCIT_C157344 @default.
- NCIT_C157344 subClassOf NCIT_C1908 @default.
- NCIT_C157344 subClassOf NCIT_C1909 @default.
- NCIT_C157344 subClassOf NCIT_C28681 @default.
- NCIT_C157344 subClassOf NCIT_C307 @default.
- NCIT_C157344 subClassOf NCIT_C308 @default.