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- NCIT_C157538 IAO_0000115 "A fixed combination of emtricitabine, a nucleoside reverse transcriptase (RT) inhibitor (NRTI) analog of cytidine and tenofovir alafenamide fumarate, the fumarate salt form of the lipophilic phosphonamidate prodrug of tenofovir, a NRTI analog of adenosine monophosphate, that is used to treat human immunodeficiency virus (HIV) infection. Upon oral administration, emtricitabine and tenofovir inhibit the activity of HIV RT by competing with natural deoxyribonucleosides for incorporation into the growing viral DNA chain resulting in early chain termination. This interferes with the generation of DNA copies of viral RNA, which is necessary for the synthesis of new virions." @default.
- NCIT_C157538 NCIT_NHC0 "C157538" @default.
- NCIT_C157538 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C157538 NCIT_P108 "Emtricitabine/Tenofovir Alafenamide Fumarate" @default.
- NCIT_C157538 NCIT_P208 "CL937256" @default.
- NCIT_C157538 normalizedInformationContent "100" @default.
- NCIT_C157538 referenceCount "1" @default.
- NCIT_C157538 hasExactSynonym "Descovy" @default.
- NCIT_C157538 hasExactSynonym "Emtricitabine/Tenofovir Alafenamide Fumarate" @default.
- NCIT_C157538 hasExactSynonym "Emtricitabine/Tenofovir Alafenamide" @default.
- NCIT_C157538 hasExactSynonym "FTC/TAF" @default.
- NCIT_C157538 inSubset NCIT_C173381 @default.
- NCIT_C157538 inSubset NCIT_C173383 @default.
- NCIT_C157538 type Class @default.
- NCIT_C157538 isDefinedBy ncit.owl @default.
- NCIT_C157538 label "Emtricitabine/Tenofovir Alafenamide Fumarate" @default.
- NCIT_C157538 subClassOf NCIT_C157538 @default.
- NCIT_C157538 subClassOf NCIT_C1589 @default.
- NCIT_C157538 subClassOf NCIT_C1660 @default.
- NCIT_C157538 subClassOf NCIT_C1908 @default.
- NCIT_C157538 subClassOf NCIT_C1909 @default.
- NCIT_C157538 subClassOf NCIT_C254 @default.
- NCIT_C157538 subClassOf NCIT_C281 @default.
- NCIT_C157538 subClassOf NCIT_C471 @default.