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- NCIT_C158509 IAO_0000115 "A radioconjugate composed of an optimized affibody labeled with technetium Tc 99m, with potential use as a tracer for human epidermal growth factor receptor type 2 (HER2; ErbB2)-expressing tumors using single photon emission computed tomography (SPECT). Upon administration, the Tc 99m-labeled affibody ABH2 targets and binds to HER2-expressing tumor cells. This facilitates both detection of HER2-expressing tumor cells and assessment of responses to HER2-targeting chemotherapeutic agents using SPECT. HER2, a receptor tyrosine kinase, is mutated in many tumor cell types and plays a key role in tumor cell proliferation and tumor vascularization." @default.
- NCIT_C158509 NCIT_NHC0 "C158509" @default.
- NCIT_C158509 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C158509 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C158509 NCIT_P108 "Technetium Tc-99m Anti-HER2 Affibody ABH2" @default.
- NCIT_C158509 NCIT_P208 "CL938050" @default.
- NCIT_C158509 NCIT_P329 "797157" @default.
- NCIT_C158509 NCIT_P330 "797157" @default.
- NCIT_C158509 NCIT_P399 "797157" @default.
- NCIT_C158509 normalizedInformationContent "100" @default.
- NCIT_C158509 referenceCount "1" @default.
- NCIT_C158509 hasExactSynonym "99mTc-ABH2" @default.
- NCIT_C158509 hasExactSynonym "HER2-targeting 99mTc-labeled Affibody" @default.
- NCIT_C158509 hasExactSynonym "Technetium Tc-99m Anti-HER2 Affibody ABH2" @default.
- NCIT_C158509 inSubset NCIT_C176424 @default.
- NCIT_C158509 type Class @default.
- NCIT_C158509 isDefinedBy ncit.owl @default.
- NCIT_C158509 label "Technetium Tc-99m Anti-HER2 Affibody ABH2" @default.
- NCIT_C158509 subClassOf NCIT_C1446 @default.
- NCIT_C158509 subClassOf NCIT_C1511 @default.
- NCIT_C158509 subClassOf NCIT_C1512 @default.
- NCIT_C158509 subClassOf NCIT_C158509 @default.
- NCIT_C158509 subClassOf NCIT_C1908 @default.
- NCIT_C158509 subClassOf NCIT_C1909 @default.
- NCIT_C158509 subClassOf NCIT_C2124 @default.
- NCIT_C158509 subClassOf NCIT_C307 @default.
- NCIT_C158509 subClassOf NCIT_C308 @default.