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- NCIT_C158510 IAO_0000115 "An inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities. Upon intravenous administration, Bcl-2 inhibitor VOB560 binds to and inhibits the activity of Bcl-2, thereby restoring apoptotic processes in tumor cells. Bcl-2 protein is overexpressed in many cancer types and plays an important role in the negative regulation of apoptosis; its expression is associated with increased drug resistance and tumor cell survival." @default.
- NCIT_C158510 NCIT_A32 NCIT_C1909 @default.
- NCIT_C158510 NCIT_NHC0 "C158510" @default.
- NCIT_C158510 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C158510 NCIT_P107 "BCL2 Inhibitor VOB560" @default.
- NCIT_C158510 NCIT_P108 "BCL2 Inhibitor VOB560" @default.
- NCIT_C158510 NCIT_P208 "CL938051" @default.
- NCIT_C158510 NCIT_P322 "CTRP" @default.
- NCIT_C158510 NCIT_P322 "GDC" @default.
- NCIT_C158510 NCIT_P329 "797175" @default.
- NCIT_C158510 NCIT_P330 "797175" @default.
- NCIT_C158510 NCIT_P375 "Bcl-2 Inhibitor S65487" @default.
- NCIT_C158510 NCIT_P399 "797175" @default.
- NCIT_C158510 normalizedInformationContent "100" @default.
- NCIT_C158510 referenceCount "1" @default.
- NCIT_C158510 hasExactSynonym "BCL2 Inhibitor VOB560" @default.
- NCIT_C158510 hasExactSynonym "Bcl-2 Inhibitor S65487" @default.
- NCIT_C158510 hasExactSynonym "S 65487" @default.
- NCIT_C158510 hasExactSynonym "S-65487" @default.
- NCIT_C158510 hasExactSynonym "S65487" @default.
- NCIT_C158510 hasExactSynonym "VOB 560" @default.
- NCIT_C158510 hasExactSynonym "VOB-560" @default.
- NCIT_C158510 hasExactSynonym "VOB560" @default.
- NCIT_C158510 inSubset NCIT_C116977 @default.
- NCIT_C158510 inSubset NCIT_C116978 @default.
- NCIT_C158510 inSubset NCIT_C128784 @default.
- NCIT_C158510 inSubset NCIT_C157711 @default.
- NCIT_C158510 inSubset NCIT_C157712 @default.
- NCIT_C158510 inSubset NCIT_C176424 @default.
- NCIT_C158510 inSubset NCIT_C177537 @default.
- NCIT_C158510 type Class @default.
- NCIT_C158510 isDefinedBy ncit.owl @default.
- NCIT_C158510 label "BCL2 Inhibitor VOB560" @default.
- NCIT_C158510 subClassOf NCIT_C129839 @default.
- NCIT_C158510 subClassOf NCIT_C158510 @default.
- NCIT_C158510 subClassOf NCIT_C159200 @default.
- NCIT_C158510 subClassOf NCIT_C163758 @default.
- NCIT_C158510 subClassOf NCIT_C1908 @default.
- NCIT_C158510 subClassOf NCIT_C1909 @default.
- NCIT_C158510 subClassOf NCIT_C192025 @default.
- NCIT_C158510 subClassOf NCIT_C274 @default.