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- NCIT_C158511 IAO_0000115 "An alkyl polyglycol ether of lauryl alcohol with sclerosing and potential antineoplastic activities. Upon intralesional administration, polidocanol induces endothelial cell injury by disrupting calcium signaling and nitric oxide pathways. Following endothelial damage, platelets aggregate at the site of injury and attach to the venous wall, resulting in a dense network of platelets, cellular debris, and fibrin that occludes the vessel. Inducing endothelial cell damage within melanoma metastases may incite an antitumor response in untreated bystander lesions and inhibit the growth of in transit metastases and other cutaneous lesions." @default.
- NCIT_C158511 NCIT_A32 NCIT_C1909 @default.
- NCIT_C158511 NCIT_NHC0 "C158511" @default.
- NCIT_C158511 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C158511 NCIT_P108 "Polidocanol" @default.
- NCIT_C158511 NCIT_P208 "CL563467" @default.
- NCIT_C158511 NCIT_P210 "3055-99-0" @default.
- NCIT_C158511 NCIT_P319 "0AWH8BFG9A" @default.
- NCIT_C158511 NCIT_P322 "FDA" @default.
- NCIT_C158511 NCIT_P322 "GDC" @default.
- NCIT_C158511 NCIT_P329 "797212" @default.
- NCIT_C158511 NCIT_P330 "797212" @default.
- NCIT_C158511 NCIT_P375 "Polidocanol" @default.
- NCIT_C158511 NCIT_P399 "797212" @default.
- NCIT_C158511 normalizedInformationContent "100" @default.
- NCIT_C158511 referenceCount "1" @default.
- NCIT_C158511 hasExactSynonym "Aethoxysklerol" @default.
- NCIT_C158511 hasExactSynonym "Asclera" @default.
- NCIT_C158511 hasExactSynonym "Dodecylnonaoxyethylene Glycol Monoether" @default.
- NCIT_C158511 hasExactSynonym "Laureth 9" @default.
- NCIT_C158511 hasExactSynonym "Laureth-9" @default.
- NCIT_C158511 hasExactSynonym "Lauromacrogol 400" @default.
- NCIT_C158511 hasExactSynonym "Nonaethylene Glycol Monododecyl Ether" @default.
- NCIT_C158511 hasExactSynonym "POLIDOCANOL" @default.
- NCIT_C158511 hasExactSynonym "Polidocanol" @default.
- NCIT_C158511 inSubset NCIT_C128784 @default.
- NCIT_C158511 inSubset NCIT_C157711 @default.
- NCIT_C158511 inSubset NCIT_C157712 @default.
- NCIT_C158511 inSubset NCIT_C176424 @default.
- NCIT_C158511 inSubset NCIT_C177537 @default.
- NCIT_C158511 inSubset NCIT_C63923 @default.
- NCIT_C158511 type Class @default.
- NCIT_C158511 isDefinedBy ncit.owl @default.
- NCIT_C158511 label "Polidocanol" @default.
- NCIT_C158511 subClassOf NCIT_C158511 @default.
- NCIT_C158511 subClassOf NCIT_C1908 @default.
- NCIT_C158511 subClassOf NCIT_C1909 @default.
- NCIT_C158511 subClassOf NCIT_C2196 @default.
- NCIT_C158511 subClassOf NCIT_C274 @default.
- NCIT_C158511 subClassOf NCIT_C78274 @default.