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- NCIT_C1588 IAO_0000115 "The sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV). Ganciclovir sodium is a prodrug that is phosphorylated and subsequently converted into its triphosphate form, the active metabolite ganciclovir-5-triphosphate (ganciclovir-TP), in the infected cells by cellular kinases. Ganciclovir-TP competes as a substrate with nucleotide triphosphates for viral DNA polymerase. Once it gets incorporated into DNA strand, it prevents further polymerization of DNA, thereby interfering with viral DNA replication." @default.
- NCIT_C1588 NCIT_A6 NCIT_C517 @default.
- NCIT_C1588 NCIT_NHC0 "C1588" @default.
- NCIT_C1588 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C1588 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1588 NCIT_P108 "Ganciclovir Sodium" @default.
- NCIT_C1588 NCIT_P207 "C0282399" @default.
- NCIT_C1588 NCIT_P210 "107910-75-8" @default.
- NCIT_C1588 NCIT_P319 "02L083W284" @default.
- NCIT_C1588 NCIT_P322 "FDA" @default.
- NCIT_C1588 NCIT_P350 "C9H12N5O4.Na" @default.
- NCIT_C1588 NCIT_P366 "Ganciclovir_Sodium" @default.
- NCIT_C1588 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C1588 referenceCount "5" @default.
- NCIT_C1588 hasExactSynonym "9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, Monosodium Salt" @default.
- NCIT_C1588 hasExactSynonym "BIOLF-62" @default.
- NCIT_C1588 hasExactSynonym "BW-759" @default.
- NCIT_C1588 hasExactSynonym "BW-759U" @default.
- NCIT_C1588 hasExactSynonym "Cymevene" @default.
- NCIT_C1588 hasExactSynonym "Cytovene" @default.
- NCIT_C1588 hasExactSynonym "Cytovene-IV" @default.
- NCIT_C1588 hasExactSynonym "DHPG Sodium" @default.
- NCIT_C1588 hasExactSynonym "DHPG sodium" @default.
- NCIT_C1588 hasExactSynonym "Denosine" @default.
- NCIT_C1588 hasExactSynonym "GANCICLOVIR SODIUM" @default.
- NCIT_C1588 hasExactSynonym "GCV Sodium" @default.
- NCIT_C1588 hasExactSynonym "GCV sodium" @default.
- NCIT_C1588 hasExactSynonym "Ganciclovir Sodium" @default.
- NCIT_C1588 hasExactSynonym "Ganciclovir sodium" @default.
- NCIT_C1588 hasExactSynonym "RS-21592 Sodium" @default.
- NCIT_C1588 inSubset NCIT_C63923 @default.
- NCIT_C1588 type Class @default.
- NCIT_C1588 isDefinedBy ncit.owl @default.
- NCIT_C1588 label "Ganciclovir Sodium" @default.
- NCIT_C1588 subClassOf NCIT_C1588 @default.
- NCIT_C1588 subClassOf NCIT_C1908 @default.
- NCIT_C1588 subClassOf NCIT_C1909 @default.
- NCIT_C1588 subClassOf NCIT_C254 @default.
- NCIT_C1588 subClassOf NCIT_C281 @default.
- NCIT_C1588 subClassOf NCIT_C29575 @default.
- NCIT_C1588 subClassOf NCIT_C471 @default.