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- NCIT_C1594 IAO_0000115 "An antineoplastic antibiotic that is structurally similar to the benzoquinone ansamycin antibiotic geldanamycin. A geldanamycin analogue binds to HSP90, a chaperone protein that aids in the assembly, maturation, and folding of proteins. Subsequently, the function of HSP90 is inhibited, leading to the degradation and depletion of client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction." @default.
- NCIT_C1594 NCIT_A7 NCIT_C17766 @default.
- NCIT_C1594 NCIT_NHC0 "C1594" @default.
- NCIT_C1594 NCIT_P106 "Chemical Viewed Functionally" @default.
- NCIT_C1594 NCIT_P107 "Anthracycline Antineoplastic Antibiotic" @default.
- NCIT_C1594 NCIT_P108 "Anthracycline Antineoplastic Antibiotic" @default.
- NCIT_C1594 NCIT_P207 "C0282564" @default.
- NCIT_C1594 NCIT_P322 "CTRP" @default.
- NCIT_C1594 NCIT_P325 "A type of antibiotic that comes from certain types of Streptomyces bacteria. Anthracyclines are used to treat many types of cancer. Anthracyclines damage the DNA in cancer cells, causing them to die. Daunorubicin, doxorubicin, and epirubicin are anthracyclines." @default.
- NCIT_C1594 NCIT_P366 "Anthracycline_Antibiotic" @default.
- NCIT_C1594 NCIT_P368 "CHEBI:49322" @default.
- NCIT_C1594 normalizedInformationContent "54.01167304478998" @default.
- NCIT_C1594 referenceCount "1043" @default.
- NCIT_C1594 hasExactSynonym "Anthracycline Antineoplastic Antibiotic" @default.
- NCIT_C1594 hasExactSynonym "Anthracyclines" @default.
- NCIT_C1594 hasExactSynonym "Chemotherapy, Cancer, Anthracyclines" @default.
- NCIT_C1594 hasExactSynonym "anthracycline" @default.
- NCIT_C1594 inSubset NCIT_C116977 @default.
- NCIT_C1594 inSubset NCIT_C116978 @default.
- NCIT_C1594 type Class @default.
- NCIT_C1594 isDefinedBy ncit.owl @default.
- NCIT_C1594 label "Anthracycline Antineoplastic Antibiotic" @default.
- NCIT_C1594 subClassOf NCIT_C129824 @default.
- NCIT_C1594 subClassOf NCIT_C129825 @default.
- NCIT_C1594 subClassOf NCIT_C1594 @default.
- NCIT_C1594 subClassOf NCIT_C1748 @default.
- NCIT_C1594 subClassOf NCIT_C186664 @default.
- NCIT_C1594 subClassOf NCIT_C1908 @default.
- NCIT_C1594 subClassOf NCIT_C1909 @default.
- NCIT_C1594 subClassOf NCIT_C1968 @default.
- NCIT_C1594 subClassOf NCIT_C2115 @default.
- NCIT_C1594 subClassOf NCIT_C2161 @default.
- NCIT_C1594 subClassOf NCIT_C2189 @default.
- NCIT_C1594 subClassOf NCIT_C259 @default.
- NCIT_C1594 subClassOf NCIT_C274 @default.
- NCIT_C1594 subClassOf NCIT_C2842 @default.
- NCIT_C1594 subClassOf NCIT_C471 @default.