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- NCIT_C159537 IAO_0000115 "A radiopharmaceutical composed of biodegradable calcium carbonate microspheres labeled with the alpha-emitting radioisotope radium Ra 224, with antineoplastic activity. Upon intraperitoneal (IP) administration of the radium Ra 224-labeled calcium carbonate microparticles, Ra 224 kills tumor cells through local emission of high energy alpha particles, causing DNA double-strand breaks. The short range effects of alpha emission allows for localized DNA damage with limited toxicity to nearby healthy tissue." @default.
- NCIT_C159537 NCIT_A32 NCIT_C1909 @default.
- NCIT_C159537 NCIT_NHC0 "C159537" @default.
- NCIT_C159537 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C159537 NCIT_P108 "Radium Ra 224-labeled Calcium Carbonate Microparticles" @default.
- NCIT_C159537 NCIT_P208 "CL951431" @default.
- NCIT_C159537 NCIT_P322 "GDC" @default.
- NCIT_C159537 NCIT_P329 "797476" @default.
- NCIT_C159537 NCIT_P330 "797476" @default.
- NCIT_C159537 NCIT_P375 "Radium Ra 224-labeled Calcium Carbonate Microparticles" @default.
- NCIT_C159537 NCIT_P399 "797476" @default.
- NCIT_C159537 normalizedInformationContent "100" @default.
- NCIT_C159537 referenceCount "1" @default.
- NCIT_C159537 hasExactSynonym "224Ra-labeled Calcium Carbonate Micro-particles" @default.
- NCIT_C159537 hasExactSynonym "Alpha-emitting 224Ra Calcium Carbonate Microspheres" @default.
- NCIT_C159537 hasExactSynonym "Ra-224 Alpha-emitting Calcium Carbonate Microparticles" @default.
- NCIT_C159537 hasExactSynonym "Radium Ra 224-labeled Calcium Carbonate Microparticles" @default.
- NCIT_C159537 hasExactSynonym "Radspherin" @default.
- NCIT_C159537 inSubset NCIT_C128784 @default.
- NCIT_C159537 inSubset NCIT_C157711 @default.
- NCIT_C159537 inSubset NCIT_C157712 @default.
- NCIT_C159537 inSubset NCIT_C176424 @default.
- NCIT_C159537 inSubset NCIT_C177537 @default.
- NCIT_C159537 type Class @default.
- NCIT_C159537 isDefinedBy ncit.owl @default.
- NCIT_C159537 label "Radium Ra 224-labeled Calcium Carbonate Microparticles" @default.
- NCIT_C159537 subClassOf NCIT_C129819 @default.
- NCIT_C159537 subClassOf NCIT_C1446 @default.
- NCIT_C159537 subClassOf NCIT_C159537 @default.
- NCIT_C159537 subClassOf NCIT_C1908 @default.
- NCIT_C159537 subClassOf NCIT_C1909 @default.
- NCIT_C159537 subClassOf NCIT_C200225 @default.
- NCIT_C159537 subClassOf NCIT_C2124 @default.
- NCIT_C159537 subClassOf NCIT_C274 @default.