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- NCIT_C1615 IAO_0000115 "A symmetrical dimeric bis-naphthalimide compound and a topoisomerase II inhibitor with antineoplastic activity. Elinafide contains two neutral chromophores joined by a cationic linker and is capable of bis-intercalation at the TpG and CpA steps of the DNA hexanucleotide. Intercalation inhibits topoisomerase II activity and causing DNA stand breakage, thereby leads to inhibition of DNA, RNA, and protein synthesis." @default.
- NCIT_C1615 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1615 NCIT_NHC0 "C1615" @default.
- NCIT_C1615 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1615 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1615 NCIT_P108 "Elinafide" @default.
- NCIT_C1615 NCIT_P207 "C1433453" @default.
- NCIT_C1615 NCIT_P210 "162706-37-8" @default.
- NCIT_C1615 NCIT_P319 "HL580335SI" @default.
- NCIT_C1615 NCIT_P322 "FDA" @default.
- NCIT_C1615 NCIT_P322 "GDC" @default.
- NCIT_C1615 NCIT_P325 "An anticancer drug that kills cancer cells by affecting DNA synthesis." @default.
- NCIT_C1615 NCIT_P329 "42578" @default.
- NCIT_C1615 NCIT_P330 "42578" @default.
- NCIT_C1615 NCIT_P350 "C31H28N4O4" @default.
- NCIT_C1615 NCIT_P366 "LU_79553" @default.
- NCIT_C1615 NCIT_P375 "Elinafide" @default.
- NCIT_C1615 NCIT_P399 "42578" @default.
- NCIT_C1615 normalizedInformationContent "100" @default.
- NCIT_C1615 referenceCount "1" @default.
- NCIT_C1615 hasExactSynonym "ELINAFIDE" @default.
- NCIT_C1615 hasExactSynonym "Elinafide" @default.
- NCIT_C1615 hasExactSynonym "LU 79553" @default.
- NCIT_C1615 hasExactSynonym "LU-79553" @default.
- NCIT_C1615 hasExactSynonym "N,N'-(Trimethylenebis(iminoethylene))dinaphthalimide" @default.
- NCIT_C1615 inSubset NCIT_C128784 @default.
- NCIT_C1615 inSubset NCIT_C157711 @default.
- NCIT_C1615 inSubset NCIT_C157712 @default.
- NCIT_C1615 inSubset NCIT_C176424 @default.
- NCIT_C1615 inSubset NCIT_C177537 @default.
- NCIT_C1615 inSubset NCIT_C63923 @default.
- NCIT_C1615 type Class @default.
- NCIT_C1615 isDefinedBy ncit.owl @default.
- NCIT_C1615 label "Elinafide" @default.
- NCIT_C1615 subClassOf NCIT_C1615 @default.
- NCIT_C1615 subClassOf NCIT_C186664 @default.
- NCIT_C1615 subClassOf NCIT_C1908 @default.
- NCIT_C1615 subClassOf NCIT_C1909 @default.
- NCIT_C1615 subClassOf NCIT_C274 @default.
- NCIT_C1615 subClassOf NCIT_C2842 @default.
- NCIT_C1615 subClassOf NCIT_C582 @default.