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- NCIT_C161600 IAO_0000115 "A bio-enhanced extract-based preparation containing curcumin, a poorly water-soluble phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties, including antineoplastic, chemopreventive, antioxidant, anti-angiogenic, neuroprotective and anti-inflammatory activities. Upon oral administration, curcumin blocks the formation of reactive-oxygen species, neutralizes free radicals, and prevents oxidative stress and DNA damage. Curcumin also possesses anti-inflammatory properties as a result of inhibition of cyclooxygenases (COX) and other enzymes involved in inflammation. It disrupts various cell signal transduction pathways involved in carcinogenesis and prevents the expression of many transcription factors. In addition, curcumin modulates phase II enzymes. Altogether, this prevents and/or inhibits tumor cell formation and proliferation. Compared to the very poorly absorbed curcumin alone, this extract formulation, by micronizing curcumin and adding turmeric essential oils, has a much greater bioavailability, an improved pharmacokinetic profile and increased efficacy." @default.
- NCIT_C161600 NCIT_NHC0 "C161600" @default.
- NCIT_C161600 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C161600 NCIT_P107 "Bio-enhanced Curcumin Extract Formulation" @default.
- NCIT_C161600 NCIT_P108 "Bio-enhanced Curcumin Extract Formulation" @default.
- NCIT_C161600 NCIT_P208 "CL970143" @default.
- NCIT_C161600 NCIT_P322 "CTRP" @default.
- NCIT_C161600 NCIT_P329 "798439" @default.
- NCIT_C161600 NCIT_P330 "798439" @default.
- NCIT_C161600 NCIT_P399 "798439" @default.
- NCIT_C161600 normalizedInformationContent "100" @default.
- NCIT_C161600 referenceCount "1" @default.
- NCIT_C161600 hasExactSynonym "BCM-95 (R) CG" @default.
- NCIT_C161600 hasExactSynonym "BCM-95 CG Curcumin Extract" @default.
- NCIT_C161600 hasExactSynonym "BCM-95 CG Curcumin" @default.
- NCIT_C161600 hasExactSynonym "BCM-95CG" @default.
- NCIT_C161600 hasExactSynonym "BCM95 CG" @default.
- NCIT_C161600 hasExactSynonym "BCM95CG" @default.
- NCIT_C161600 hasExactSynonym "Bio-enhanced BCM-95 CG Curcumin" @default.
- NCIT_C161600 hasExactSynonym "Bio-enhanced Curcumin Extract Formulation" @default.
- NCIT_C161600 hasExactSynonym "Biocurcumax" @default.
- NCIT_C161600 hasExactSynonym "Curcumin BCM-95CG" @default.
- NCIT_C161600 inSubset NCIT_C116977 @default.
- NCIT_C161600 inSubset NCIT_C116978 @default.
- NCIT_C161600 inSubset NCIT_C176424 @default.
- NCIT_C161600 type Class @default.
- NCIT_C161600 isDefinedBy ncit.owl @default.
- NCIT_C161600 label "Bio-enhanced Curcumin Extract Formulation" @default.
- NCIT_C161600 subClassOf NCIT_C1323 @default.
- NCIT_C161600 subClassOf NCIT_C161600 @default.
- NCIT_C161600 subClassOf NCIT_C1908 @default.
- NCIT_C161600 subClassOf NCIT_C1909 @default.
- NCIT_C161600 subClassOf NCIT_C2198 @default.
- NCIT_C161600 subClassOf NCIT_C2356 @default.
- NCIT_C161600 subClassOf NCIT_C241 @default.
- NCIT_C161600 subClassOf NCIT_C257 @default.
- NCIT_C161600 subClassOf NCIT_C471 @default.
- NCIT_C161600 subClassOf NCIT_C78272 @default.