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- NCIT_C161864 IAO_0000115 "An agonistic humanized IgG1 monoclonal antibody that recognizes the co-stimulatory receptor OX40 (CD134; tumor necrosis factor receptor superfamily member 4; TNFRSF4), with potential immunostimulatory activity. Upon administration, revdofilimab selectively binds to and activates OX40. This may induce the proliferation of memory and effector T-lymphocytes and inhibit the function of T-regulatory cells (Tregs) in the tumor microenvironment (TME). OX40, a cell surface glycoprotein and member of the tumor necrosis factor receptor superfamily (TNFRSF), is expressed on T-lymphocytes and plays an essential role in T-cell activation and differentiation." @default.
- NCIT_C161864 NCIT_A32 NCIT_C1909 @default.
- NCIT_C161864 NCIT_A7 NCIT_C94790 @default.
- NCIT_C161864 NCIT_NHC0 "C161864" @default.
- NCIT_C161864 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C161864 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C161864 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C161864 NCIT_P107 "Revdofilimab" @default.
- NCIT_C161864 NCIT_P108 "Revdofilimab" @default.
- NCIT_C161864 NCIT_P208 "CL970355" @default.
- NCIT_C161864 NCIT_P210 "2230138-89-1" @default.
- NCIT_C161864 NCIT_P319 "2Y83Y2ORD3" @default.
- NCIT_C161864 NCIT_P322 "CTRP" @default.
- NCIT_C161864 NCIT_P322 "FDA" @default.
- NCIT_C161864 NCIT_P322 "GDC" @default.
- NCIT_C161864 NCIT_P329 "792559" @default.
- NCIT_C161864 NCIT_P330 "792559" @default.
- NCIT_C161864 NCIT_P375 "Anti-OX40 Agonist Monoclonal Antibody ABBV-368" @default.
- NCIT_C161864 NCIT_P375 "Revdofilimab" @default.
- NCIT_C161864 NCIT_P399 "792559" @default.
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- NCIT_C161864 NCIT_R72 NCIT_C38434 @default.
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- NCIT_C161864 NCIT_R72 NCIT_C39567 @default.
- NCIT_C161864 NCIT_R72 NCIT_C39568 @default.
- NCIT_C161864 normalizedInformationContent "100" @default.
- NCIT_C161864 referenceCount "1" @default.
- NCIT_C161864 hasExactSynonym "ABBV 368" @default.
- NCIT_C161864 hasExactSynonym "ABBV-368" @default.
- NCIT_C161864 hasExactSynonym "ABBV368" @default.
- NCIT_C161864 hasExactSynonym "Agonistic Anti-OX40 Monoclonal Antibody ABBV-368" @default.
- NCIT_C161864 hasExactSynonym "Anti-OX40 Agonist Monoclonal Antibody ABBV-368" @default.
- NCIT_C161864 hasExactSynonym "Anti-OX40 Agonistic Monoclonal Antibody ABBV-368" @default.
- NCIT_C161864 hasExactSynonym "PR1628103" @default.
- NCIT_C161864 hasExactSynonym "REVDOFILIMAB" @default.
- NCIT_C161864 hasExactSynonym "Revdofilimab" @default.
- NCIT_C161864 inSubset NCIT_C116977 @default.
- NCIT_C161864 inSubset NCIT_C116978 @default.
- NCIT_C161864 inSubset NCIT_C128784 @default.
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- NCIT_C161864 inSubset NCIT_C63923 @default.
- NCIT_C161864 type Class @default.
- NCIT_C161864 isDefinedBy ncit.owl @default.
- NCIT_C161864 label "Revdofilimab" @default.
- NCIT_C161864 subClassOf Baa228aa352a1fec65783241f727334f2 @default.
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- NCIT_C161864 subClassOf NCIT_C141144 @default.
- NCIT_C161864 subClassOf NCIT_C161864 @default.
- NCIT_C161864 subClassOf NCIT_C1908 @default.
- NCIT_C161864 subClassOf NCIT_C1909 @default.
- NCIT_C161864 subClassOf NCIT_C20401 @default.
- NCIT_C161864 subClassOf NCIT_C274 @default.
- NCIT_C161864 subClassOf NCIT_C307 @default.
- NCIT_C161864 subClassOf NCIT_C308 @default.
- NCIT_C161864 subClassOf NCIT_C96040 @default.