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- NCIT_C162348 IAO_0000115 "The anhydrous, mesylate salt form of exatecan, a semisynthetic, water-soluble derivative of camptothecin, with antineoplastic activity. Upon administration, exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting re-ligation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death." @default.
- NCIT_C162348 NCIT_A32 NCIT_C1909 @default.
- NCIT_C162348 NCIT_A6 NCIT_C66720 @default.
- NCIT_C162348 NCIT_NHC0 "C162348" @default.
- NCIT_C162348 NCIT_P106 "Organic Chemical" @default.
- NCIT_C162348 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C162348 NCIT_P108 "Exatecan Mesylate Anhydrous" @default.
- NCIT_C162348 NCIT_P208 "CL970851" @default.
- NCIT_C162348 NCIT_P210 "169869-90-3" @default.
- NCIT_C162348 NCIT_P319 "Y76278R9RJ" @default.
- NCIT_C162348 NCIT_P322 "FDA" @default.
- NCIT_C162348 NCIT_P322 "GDC" @default.
- NCIT_C162348 NCIT_P375 "Exatecan Mesylate Anhydrous" @default.
- NCIT_C162348 normalizedInformationContent "100" @default.
- NCIT_C162348 referenceCount "1" @default.
- NCIT_C162348 hasExactSynonym "10H,13H-Benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S,9S)-, Methanesulfonate (1:1)" @default.
- NCIT_C162348 hasExactSynonym "EXATECAN MESYLATE ANHYDROUS" @default.
- NCIT_C162348 hasExactSynonym "Exatecan Mesylate Anhydrous" @default.
- NCIT_C162348 inSubset NCIT_C128784 @default.
- NCIT_C162348 inSubset NCIT_C157711 @default.
- NCIT_C162348 inSubset NCIT_C157712 @default.
- NCIT_C162348 inSubset NCIT_C177537 @default.
- NCIT_C162348 inSubset NCIT_C63923 @default.
- NCIT_C162348 type Class @default.
- NCIT_C162348 isDefinedBy ncit.owl @default.
- NCIT_C162348 label "Exatecan Mesylate Anhydrous" @default.
- NCIT_C162348 subClassOf NCIT_C129824 @default.
- NCIT_C162348 subClassOf NCIT_C129825 @default.
- NCIT_C162348 subClassOf NCIT_C162348 @default.
- NCIT_C162348 subClassOf NCIT_C1748 @default.
- NCIT_C162348 subClassOf NCIT_C1904 @default.
- NCIT_C162348 subClassOf NCIT_C1908 @default.
- NCIT_C162348 subClassOf NCIT_C1909 @default.
- NCIT_C162348 subClassOf NCIT_C2189 @default.
- NCIT_C162348 subClassOf NCIT_C274 @default.
- NCIT_C162348 subClassOf NCIT_C2843 @default.
- NCIT_C162348 subClassOf NCIT_C471 @default.