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- NCIT_C162563 IAO_0000115 "A radioconjugate composed of rituximab, a recombinant chimeric murine/human immunoglobulin G1 (IgG1) antibody directed against the CD20 antigen, conjugated to the beta-emitting radioisotope lutetium Lu 177, with potential antineoplastic activity. Upon administration, the rituximab moiety targets and binds to CD20 expressed on tumor cells and delivers a cytotoxic dose of beta radiation to CD20-expressing cells. CD20 is expressed on the surface of pre-B and mature B-lymphocytes and is overexpressed in a variety of B-cell malignancies." @default.
- NCIT_C162563 NCIT_A32 NCIT_C1909 @default.
- NCIT_C162563 NCIT_NHC0 "C162563" @default.
- NCIT_C162563 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C162563 NCIT_P108 "Lutetium Lu-177 Rituximab" @default.
- NCIT_C162563 NCIT_P208 "CL971073" @default.
- NCIT_C162563 NCIT_P322 "GDC" @default.
- NCIT_C162563 NCIT_P375 "Lutetium Lu-177 Rituximab" @default.
- NCIT_C162563 normalizedInformationContent "100" @default.
- NCIT_C162563 referenceCount "1" @default.
- NCIT_C162563 hasExactSynonym "177Lu-Rituximab" @default.
- NCIT_C162563 hasExactSynonym "Lutetium Lu-177 Rituximab" @default.
- NCIT_C162563 hasExactSynonym "Lutetium-177 Labeled Rituximab" @default.
- NCIT_C162563 inSubset NCIT_C128784 @default.
- NCIT_C162563 inSubset NCIT_C157711 @default.
- NCIT_C162563 inSubset NCIT_C157712 @default.
- NCIT_C162563 inSubset NCIT_C177537 @default.
- NCIT_C162563 type Class @default.
- NCIT_C162563 isDefinedBy ncit.owl @default.
- NCIT_C162563 label "Lutetium Lu-177 Rituximab" @default.
- NCIT_C162563 subClassOf NCIT_C129819 @default.
- NCIT_C162563 subClassOf NCIT_C1446 @default.
- NCIT_C162563 subClassOf NCIT_C162563 @default.
- NCIT_C162563 subClassOf NCIT_C1908 @default.
- NCIT_C162563 subClassOf NCIT_C1909 @default.
- NCIT_C162563 subClassOf NCIT_C2124 @default.
- NCIT_C162563 subClassOf NCIT_C274 @default.