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- NCIT_C162568 IAO_0000115 "The mesylate salt of infigratinib, an orally bioavailable pan-inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. Upon administration, infigratinib selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. FGFRs are a family of receptor tyrosine kinases which may be upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival." @default.
- NCIT_C162568 NCIT_A32 NCIT_C1909 @default.
- NCIT_C162568 NCIT_NHC0 "C162568" @default.
- NCIT_C162568 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C162568 NCIT_P108 "Infigratinib Mesylate" @default.
- NCIT_C162568 NCIT_P208 "CL971083" @default.
- NCIT_C162568 NCIT_P210 "1310746-12-3" @default.
- NCIT_C162568 NCIT_P319 "E223Z0KWCC" @default.
- NCIT_C162568 NCIT_P322 "FDA" @default.
- NCIT_C162568 NCIT_P322 "GDC" @default.
- NCIT_C162568 NCIT_P375 "Infigratinib Mesylate" @default.
- NCIT_C162568 normalizedInformationContent "100" @default.
- NCIT_C162568 referenceCount "1" @default.
- NCIT_C162568 hasExactSynonym "BGJ 398 Mesylate" @default.
- NCIT_C162568 hasExactSynonym "BGJ-398 Mesylate" @default.
- NCIT_C162568 hasExactSynonym "INFIGRATINIB MESYLATE" @default.
- NCIT_C162568 hasExactSynonym "Infigratinib Mesylate" @default.
- NCIT_C162568 inSubset NCIT_C128784 @default.
- NCIT_C162568 inSubset NCIT_C157711 @default.
- NCIT_C162568 inSubset NCIT_C157712 @default.
- NCIT_C162568 inSubset NCIT_C177537 @default.
- NCIT_C162568 inSubset NCIT_C63923 @default.
- NCIT_C162568 type Class @default.
- NCIT_C162568 isDefinedBy ncit.owl @default.
- NCIT_C162568 label "Infigratinib Mesylate" @default.
- NCIT_C162568 subClassOf NCIT_C129824 @default.
- NCIT_C162568 subClassOf NCIT_C129825 @default.
- NCIT_C162568 subClassOf NCIT_C1404 @default.
- NCIT_C162568 subClassOf NCIT_C155727 @default.
- NCIT_C162568 subClassOf NCIT_C162568 @default.
- NCIT_C162568 subClassOf NCIT_C163758 @default.
- NCIT_C162568 subClassOf NCIT_C164035 @default.
- NCIT_C162568 subClassOf NCIT_C1742 @default.
- NCIT_C162568 subClassOf NCIT_C1908 @default.
- NCIT_C162568 subClassOf NCIT_C1909 @default.
- NCIT_C162568 subClassOf NCIT_C1967 @default.
- NCIT_C162568 subClassOf NCIT_C2189 @default.
- NCIT_C162568 subClassOf NCIT_C274 @default.
- NCIT_C162568 subClassOf NCIT_C471 @default.