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- NCIT_C162773 IAO_0000115 "A suspension composed of uncoated, stable, submicron particles of the water-insoluble taxane paclitaxel, with potential antineoplastic activity. Upon intra-tumoral administration of the submicron particle paclitaxel sterile suspension, paclitaxel binds to tubulin and inhibits the disassembly of microtubules, which leads to the inhibition of cell division, thereby halting the proliferation of rapidly-dividing tumor cells. The submicron particle paclitaxel is produced through a specific proprietary method of submicron particle production without the need for coating agents or carriers and allows for prolonged retention and sustained release at the tumor site." @default.
- NCIT_C162773 NCIT_A32 NCIT_C1909 @default.
- NCIT_C162773 NCIT_A7 NCIT_C17219 @default.
- NCIT_C162773 NCIT_A7 NCIT_C18115 @default.
- NCIT_C162773 NCIT_NHC0 "C162773" @default.
- NCIT_C162773 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C162773 NCIT_P107 "Submicron Particle Paclitaxel Sterile Suspension" @default.
- NCIT_C162773 NCIT_P108 "Submicron Particle Paclitaxel Sterile Suspension" @default.
- NCIT_C162773 NCIT_P208 "CL973205" @default.
- NCIT_C162773 NCIT_P322 "CTRP" @default.
- NCIT_C162773 NCIT_P322 "GDC" @default.
- NCIT_C162773 NCIT_P329 "799071" @default.
- NCIT_C162773 NCIT_P330 "799071" @default.
- NCIT_C162773 NCIT_P375 "Submicron Particle Paclitaxel Sterile Suspension" @default.
- NCIT_C162773 NCIT_P399 "799071" @default.
- NCIT_C162773 NCIT_R124 NCIT_C17828 @default.
- NCIT_C162773 NCIT_R124 NCIT_C20480 @default.
- NCIT_C162773 NCIT_R124 NCIT_C40795 @default.
- NCIT_C162773 NCIT_R124 NCIT_C40798 @default.
- NCIT_C162773 normalizedInformationContent "100" @default.
- NCIT_C162773 referenceCount "1" @default.
- NCIT_C162773 hasExactSynonym "NanoPac" @default.
- NCIT_C162773 hasExactSynonym "Sterile Nanoparticle-based Paclitaxel Suspension" @default.
- NCIT_C162773 hasExactSynonym "Sterile Nanoparticulate Paclitaxel" @default.
- NCIT_C162773 hasExactSynonym "Submicron Particle Paclitaxel Formulation" @default.
- NCIT_C162773 hasExactSynonym "Submicron Particle Paclitaxel Sterile Suspension" @default.
- NCIT_C162773 hasExactSynonym "Submicron Particle Paclitaxel" @default.
- NCIT_C162773 inSubset NCIT_C116977 @default.
- NCIT_C162773 inSubset NCIT_C116978 @default.
- NCIT_C162773 inSubset NCIT_C128784 @default.
- NCIT_C162773 inSubset NCIT_C157711 @default.
- NCIT_C162773 inSubset NCIT_C157712 @default.
- NCIT_C162773 inSubset NCIT_C176424 @default.
- NCIT_C162773 inSubset NCIT_C177537 @default.
- NCIT_C162773 type Class @default.
- NCIT_C162773 isDefinedBy ncit.owl @default.
- NCIT_C162773 label "Submicron Particle Paclitaxel Sterile Suspension" @default.
- NCIT_C162773 subClassOf NCIT_C162773 @default.
- NCIT_C162773 subClassOf NCIT_C186664 @default.
- NCIT_C162773 subClassOf NCIT_C1908 @default.
- NCIT_C162773 subClassOf NCIT_C1909 @default.
- NCIT_C162773 subClassOf NCIT_C25974 @default.
- NCIT_C162773 subClassOf NCIT_C273 @default.
- NCIT_C162773 subClassOf NCIT_C274 @default.
- NCIT_C162773 subClassOf NCIT_C61078 @default.
- NCIT_C162773 subClassOf NCIT_C67437 @default.