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- NCIT_C162860 IAO_0000115 "A radioimmunoconjugate composed of envafolimab, a monoclonal antibody directed against programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274) and labeled with the radioisotope zirconium Zr 89, with potential use for assessing PD-L1 tumor antigen expression using positron emission tomography (PET). Upon administration of zirconium Zr 89-labeled envafolimab, the envafolimab moiety targets and binds to the PD-L1 expressed on certain tumor cells. Upon uptake and PET imaging, the radioisotope moiety can be visualized and the extent of PD-L1 expression can be assessed. This can be used to predict the therapeutic response to envafolimab and other PD-L1-targeting agents." @default.
- NCIT_C162860 NCIT_NHC0 "C162860" @default.
- NCIT_C162860 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C162860 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C162860 NCIT_P108 "Zirconium Zr 89-labeled Envafolimab" @default.
- NCIT_C162860 NCIT_P208 "CL973346" @default.
- NCIT_C162860 NCIT_P329 "798912" @default.
- NCIT_C162860 NCIT_P330 "798912" @default.
- NCIT_C162860 NCIT_P366 "Zirconium-Zr_89_Cetuximab" @default.
- NCIT_C162860 NCIT_P399 "798912" @default.
- NCIT_C162860 normalizedInformationContent "100" @default.
- NCIT_C162860 referenceCount "1" @default.
- NCIT_C162860 hasExactSynonym "89Zr-Envafolimab" @default.
- NCIT_C162860 hasExactSynonym "89Zr-KN035" @default.
- NCIT_C162860 hasExactSynonym "Zirconium Zr 89-Anti-PD-L1 Monoclonal Antibody KN035" @default.
- NCIT_C162860 hasExactSynonym "Zirconium Zr 89-Envafolimab" @default.
- NCIT_C162860 hasExactSynonym "Zirconium Zr 89-KN035" @default.
- NCIT_C162860 hasExactSynonym "Zirconium Zr 89-labeled Envafolimab" @default.
- NCIT_C162860 inSubset NCIT_C176424 @default.
- NCIT_C162860 type Class @default.
- NCIT_C162860 isDefinedBy ncit.owl @default.
- NCIT_C162860 label "Zirconium Zr 89-labeled Envafolimab" @default.
- NCIT_C162860 subClassOf NCIT_C1446 @default.
- NCIT_C162860 subClassOf NCIT_C1511 @default.
- NCIT_C162860 subClassOf NCIT_C1512 @default.
- NCIT_C162860 subClassOf NCIT_C162860 @default.
- NCIT_C162860 subClassOf NCIT_C1908 @default.
- NCIT_C162860 subClassOf NCIT_C1909 @default.
- NCIT_C162860 subClassOf NCIT_C2124 @default.
- NCIT_C162860 subClassOf NCIT_C307 @default.
- NCIT_C162860 subClassOf NCIT_C308 @default.