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- NCIT_C163022 IAO_0000115 "A bispecific monoclonal antibody, with potential immunomodulating and antineoplastic activities. Epcoritamab contains two antigen-recognition sites: one for human CD3, a T-cell surface antigen, and one for human CD20, a tumor-associated antigen (TAA) that is exclusively expressed on B-cells during most stages of B-cell development and is often overexpressed in B-cell malignancies. Upon administration, epcoritamab binds to both T-cells and CD20-expressing B-lineage tumor cells. The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response against the CD20-expressing tumor B-cells." @default.
- NCIT_C163022 NCIT_A32 NCIT_C1909 @default.
- NCIT_C163022 NCIT_NHC0 "C163022" @default.
- NCIT_C163022 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C163022 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C163022 NCIT_P107 "Epcoritamab" @default.
- NCIT_C163022 NCIT_P108 "Epcoritamab" @default.
- NCIT_C163022 NCIT_P208 "CL973375" @default.
- NCIT_C163022 NCIT_P210 "2134641-34-0" @default.
- NCIT_C163022 NCIT_P319 "D6OMY2L0WA" @default.
- NCIT_C163022 NCIT_P322 "CTRP" @default.
- NCIT_C163022 NCIT_P322 "FDA" @default.
- NCIT_C163022 NCIT_P322 "GDC" @default.
- NCIT_C163022 NCIT_P329 "798973" @default.
- NCIT_C163022 NCIT_P330 "798973" @default.
- NCIT_C163022 NCIT_P375 "Anti-CD3/CD20 Bispecific Antibody GEN3013" @default.
- NCIT_C163022 NCIT_P375 "Epcoritamab" @default.
- NCIT_C163022 NCIT_P399 "798973" @default.
- NCIT_C163022 NCIT_R124 NCIT_C17710 @default.
- NCIT_C163022 NCIT_R124 NCIT_C17828 @default.
- NCIT_C163022 NCIT_R124 NCIT_C18219 @default.
- NCIT_C163022 NCIT_R124 NCIT_C19986 @default.
- NCIT_C163022 NCIT_R124 NCIT_C40474 @default.
- NCIT_C163022 normalizedInformationContent "100" @default.
- NCIT_C163022 referenceCount "1" @default.
- NCIT_C163022 hasExactSynonym "Anti-CD20/CD3 Bispecific Antibody GEN3013" @default.
- NCIT_C163022 hasExactSynonym "DuoBody-CD3xCD20" @default.
- NCIT_C163022 hasExactSynonym "EPCORITAMAB" @default.
- NCIT_C163022 hasExactSynonym "Epcoritamab" @default.
- NCIT_C163022 hasExactSynonym "Epcoritamab-bysp" @default.
- NCIT_C163022 hasExactSynonym "Epkinly" @default.
- NCIT_C163022 hasExactSynonym "GEN 3013" @default.
- NCIT_C163022 hasExactSynonym "GEN-3013" @default.
- NCIT_C163022 hasExactSynonym "GEN3013" @default.
- NCIT_C163022 inSubset NCIT_C116977 @default.
- NCIT_C163022 inSubset NCIT_C116978 @default.
- NCIT_C163022 inSubset NCIT_C128784 @default.
- NCIT_C163022 inSubset NCIT_C157711 @default.
- NCIT_C163022 inSubset NCIT_C157712 @default.
- NCIT_C163022 inSubset NCIT_C176424 @default.
- NCIT_C163022 inSubset NCIT_C177537 @default.
- NCIT_C163022 inSubset NCIT_C63923 @default.
- NCIT_C163022 type Class @default.
- NCIT_C163022 isDefinedBy ncit.owl @default.
- NCIT_C163022 label "Epcoritamab" @default.
- NCIT_C163022 subClassOf NCIT_C112883 @default.
- NCIT_C163022 subClassOf NCIT_C129821 @default.
- NCIT_C163022 subClassOf NCIT_C129822 @default.
- NCIT_C163022 subClassOf NCIT_C141215 @default.
- NCIT_C163022 subClassOf NCIT_C1454 @default.
- NCIT_C163022 subClassOf NCIT_C163022 @default.
- NCIT_C163022 subClassOf NCIT_C163758 @default.
- NCIT_C163022 subClassOf NCIT_C164034 @default.
- NCIT_C163022 subClassOf NCIT_C1908 @default.
- NCIT_C163022 subClassOf NCIT_C1909 @default.
- NCIT_C163022 subClassOf NCIT_C200711 @default.
- NCIT_C163022 subClassOf NCIT_C201282 @default.
- NCIT_C163022 subClassOf NCIT_C20401 @default.
- NCIT_C163022 subClassOf NCIT_C274 @default.
- NCIT_C163022 subClassOf NCIT_C28227 @default.
- NCIT_C163022 subClassOf NCIT_C307 @default.
- NCIT_C163022 subClassOf NCIT_C308 @default.