Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C163762> ?p ?o ?g. }
Showing items 1 to 31 of
31
with 100 items per page.
- NCIT_C163762 IAO_0000115 "A radioimmunoconjugate composed of TAK-164, an antibody-drug conjugate (ADC) comprised of a full-length, human immunoglobulin G1 (IgG1) monoclonal antibody (mAb) directed against the extracellular domain of guanylyl cyclase C (GCC; GUCY2C) conjugated to the DNA alkylator DGN549 (IGN-P1), and linked to the radioisotope zirconium Zr 89 (Zr89), with potential use in imaging of GCC-expressing tumor cells upon positron emission tomography (PET). Upon administration of zirconium Zr 89-TAK-164, the TAK-164 moiety targets and binds to GCC. After binding, Zr89 facilitates the visualization and detection of GCC-expressing tumor cells using PET. This assesses GCC-expression and may predict or evaluate the tumor's response to TAK-164." @default.
- NCIT_C163762 NCIT_A7 NCIT_C123877 @default.
- NCIT_C163762 NCIT_NHC0 "C163762" @default.
- NCIT_C163762 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C163762 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C163762 NCIT_P107 "Zirconium Zr 89-TAK-164" @default.
- NCIT_C163762 NCIT_P108 "Zirconium Zr 89-TAK-164" @default.
- NCIT_C163762 NCIT_P208 "CL976998" @default.
- NCIT_C163762 NCIT_P322 "CTRP" @default.
- NCIT_C163762 NCIT_P329 "799309" @default.
- NCIT_C163762 NCIT_P330 "799309" @default.
- NCIT_C163762 NCIT_P399 "799309" @default.
- NCIT_C163762 normalizedInformationContent "100" @default.
- NCIT_C163762 referenceCount "1" @default.
- NCIT_C163762 hasExactSynonym "89Zr-TAK-164" @default.
- NCIT_C163762 hasExactSynonym "Zirconium Zr 89-TAK-164" @default.
- NCIT_C163762 inSubset NCIT_C116977 @default.
- NCIT_C163762 inSubset NCIT_C116978 @default.
- NCIT_C163762 inSubset NCIT_C176424 @default.
- NCIT_C163762 type Class @default.
- NCIT_C163762 isDefinedBy ncit.owl @default.
- NCIT_C163762 label "Zirconium Zr 89-TAK-164" @default.
- NCIT_C163762 subClassOf NCIT_C1446 @default.
- NCIT_C163762 subClassOf NCIT_C1511 @default.
- NCIT_C163762 subClassOf NCIT_C1512 @default.
- NCIT_C163762 subClassOf NCIT_C163762 @default.
- NCIT_C163762 subClassOf NCIT_C1908 @default.
- NCIT_C163762 subClassOf NCIT_C1909 @default.
- NCIT_C163762 subClassOf NCIT_C2124 @default.
- NCIT_C163762 subClassOf NCIT_C307 @default.
- NCIT_C163762 subClassOf NCIT_C308 @default.